Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50039209
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321586(1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-pent...)
Affinity DataKi:  140nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321585(1-(2-(2-tert-butylphenyl)benzofuran-7-yl)-3-(4-(tr...)
Affinity DataKi:  400nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321584(1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-(tri...)
Affinity DataKi:  600nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321587(1-(4-butoxyphenyl)-3-(2-(2-isopropylphenyl)benzofu...)
Affinity DataKi:  640nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321588(1-(4-chlorophenyl)-3-(2-(2-isopropylphenyl)benzofu...)
Affinity DataKi:  760nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321583(1-(4-(trifluoromethoxy)phenyl)-3-(2-(2-(trifluorom...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321589(1-(4-tert-butylphenyl)-3-(2-(2-isopropylphenyl)ben...)
Affinity DataIC50:  300nMAssay Description:Displacement of [33P]2-MeS-ADP from human P2Y1 receptor expressed in human U2OS cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321586(1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-pent...)
Affinity DataIC50:  630nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321589(1-(4-tert-butylphenyl)-3-(2-(2-isopropylphenyl)ben...)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321593(1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-meth...)
Affinity DataIC50:  1.60E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321588(1-(4-chlorophenyl)-3-(2-(2-isopropylphenyl)benzofu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321587(1-(4-butoxyphenyl)-3-(2-(2-isopropylphenyl)benzofu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321585(1-(2-(2-tert-butylphenyl)benzofuran-7-yl)-3-(4-(tr...)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321584(1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(4-(tri...)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321595(1-(2-(2-isopropylphenyl)benzofuran-7-yl)-3-(3-(tri...)
Affinity DataIC50:  5.00E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321583(1-(4-(trifluoromethoxy)phenyl)-3-(2-(2-(trifluorom...)
Affinity DataIC50:  6.30E+3nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321594(1-(4-(dimethylamino)phenyl)-3-(2-(2-isopropylpheny...)
Affinity DataIC50:  1.58E+4nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321592(1-(2-(2-isopropoxyphenyl)benzofuran-7-yl)-3-(4-(tr...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321591(1-(2-(2-chlorophenyl)benzofuran-7-yl)-3-(4-(triflu...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50321590(1-(4-(trifluoromethoxy)phenyl)-3-(2-(3-(trifluorom...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonist activity at P2Y1 expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed