Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50032011
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323215BDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 10nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323216BDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 20nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323223BDBM50323223((2S,3S)-N-(4-(5-(2-cyclohexylethyl)-1,2,4-oxadiazo...)
Affinity DataIC50: 25nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323219BDBM50323219((2S,3S)-N-((S)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323220BDBM50323220((2S,3S)-N-((S)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50: 48nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323231BDBM50323231((2S,3S)-N-(4-(5-hexyl-1,2,4-oxadiazol-3-yl)benzyl)...)
Affinity DataIC50: 49nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323242BDBM50323242((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323217BDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 58nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323234BDBM50323234((2S,3S)-N-(4-(3-heptyl-1,2,4-oxadiazol-5-yl)benzyl...)
Affinity DataIC50: 61nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299328BDBM50299328((2S,3S)-3-hydroxy-N-(4-octylphenyl)pyrrolidine-2-c...)
Affinity DataIC50: 62nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323225BDBM50323225((2S,3S)-N-(4-(5-(2-cyclopentylethyl)-1,2,4-oxadiaz...)
Affinity DataIC50: 68nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323240BDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: 68nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323233BDBM50323233((2S,3S)-N-(4-(5-heptylthiazol-2-yl)benzyl)-3-hydro...)
Affinity DataIC50: 70nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323238BDBM50323238((2S,3S)-3-hydroxy-N-(4-(5-octyl-1,2,4-oxadiazol-3-...)
Affinity DataIC50: 86nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323218BDBM50323218((2S,3S)-N-((S)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50: 110nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323228BDBM50323228((2S,3S)-3-hydroxy-N-(4-(5-(1-methylcyclohexyl)-1,2...)
Affinity DataIC50: 210nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323229BDBM50323229((2S,3S)-N-(4-(5-cyclohexyl-1,2,4-oxadiazol-3-yl)be...)
Affinity DataIC50: 380nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323230BDBM50323230((2S,3S)-3-hydroxy-N-(4-(5-pentyl-1,2,4-oxadiazol-3...)
Affinity DataIC50: 430nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323237BDBM50323237((2S,3S)-N-(4-(5-heptyl-1-methyl-1H-1,2,4-triazol-3...)
Affinity DataIC50: 610nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323226BDBM50323226((2S,3S)-N-(4-(5-cycloheptyl-1,2,4-oxadiazol-3-yl)b...)
Affinity DataIC50: 620nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323222BDBM50323222((2S,3S)-3-hydroxy-N-(4-(5-phenethyl-1,2,4-oxadiazo...)
Affinity DataIC50: 720nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323235BDBM50323235((2S,3S)-N-(4-(4-heptyl-1H-1,2,3-triazol-1-yl)benzy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323232BDBM50323232((2S,3S)-N-(4-(5-heptyl-1H-pyrazol-3-yl)benzyl)-3-h...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323215BDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323217BDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323236BDBM50323236((2S,3S)-N-(4-(5-heptyl-1,3,4-oxadiazol-2-yl)benzyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323227BDBM50323227((2S,3S)-N-(4-(5-cyclopentyl-1,2,4-oxadiazol-3-yl)b...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323221BDBM50323221((2S,3S)-N-((R)-1-(4-(5-heptyl-1,2,4-oxadiazol-3-yl...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323216BDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323240BDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323216BDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323240BDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323215BDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323216BDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323217BDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323224BDBM50323224((2S,3S)-N-(4-(5-(2-cyclopropylethyl)-1,2,4-oxadiaz...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323217BDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323240BDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323240BDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323215BDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323216BDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323217BDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323240BDBM50323240((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)benzyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323215BDBM50323215((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323216BDBM50323216((2S,3S)-N-((S)-1-(4-(5-(2-cyclohexylethyl)-1,2,4-o...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323217BDBM50323217((2S,3S)-N-((S)-1-(4-(5-(2-cyclopentylethyl)-1,2,4-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323239BDBM50323239((2S,3S)-3-hydroxy-N-(4-(5-octyl-1,2,4-oxadiazol-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Genzyme

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50323241BDBM50323241((2S,3S)-N-(4-(5-heptyl-1,2,4-oxadiazol-3-yl)phenyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of sphingosine kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed