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Found 51 Enz. Inhib. hit(s) with all data for entry = 50032921
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273546(1-(3,4-Bisdifluoromethoxyphenyl)-3-phenylpropan-1-...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336543(5-(4-chlorophenyl)-3-((pyridin-2-ylsulfonyl)methyl...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273544(1-[4-Difluoromethoxy-3-(tetrahydrofuran-3-yloxy)ph...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273574(2-Cyclohexyl-1-[4-difluoromethoxy-3-(tetrahydrofur...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273548(1-(3,4-Bisdifluoromethoxyphenyl)-4-phenylbutan-1-o...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273984(4-(2-Methoxy-4-pentanoylphenoxy)piperidine-1-carbo...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273575(1-[4-Difluoromethoxy-3-(tetrahydrofuran-3-yloxy)ph...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273572(1-(3-Cyclopentyloxy-4-difluoromethoxyphenyl]-3-met...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336542(3-(1-(3-methoxy-4-(pyridin-2-yloxy)phenyl)butyl)qu...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273510(1-[4-Difluoromethoxy-3-(pyridin-2-yloxy)phenyl]but...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273987(1-[3-Methoxy-4-(tetrahydropyran-4-yloxy)phenyl]pen...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336541(CHEMBL1673336 | ethyl 2-(2-(3-(3,4-dichlorophenyl)...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336540(2-((furan-2-ylmethylsulfonyl)methyl)-4-phenylthiaz...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336539(1-(4-(difluoromethoxy)-3-(pyridin-2-yloxy)phenyl)-...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273985(1-[3-Methoxy-4-(tetrahydropyran-4-yloxy)phenyl]but...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336538(2-((2-(thiophen-2-yl)thiazol-4-yl)methyl)isoindoli...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336537(CHEMBL1673331 | N-benzyl-5-(4-cyano-3-(methylthio)...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336536(3-((furan-2-ylmethylsulfonyl)methyl)-5-(isoxazol-5...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336535(CHEMBL1673330 | ethyl 2,5-dimethyl-6-(5-phenyl-4H-...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273511(1-[4-Difluoromethoxy-3-(tetrahydropyran-4-yloxy)ph...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273508(2-Cyclohexyl-1-[4-methoxy-3-(tetrahydrofuran-3-ylo...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273331(1-[3-Methoxy-4-(tetrahydrofuran-3-yloxy)phenyl]pen...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273543(CHEMBL457662 | Cyclohexyl-1-[4-difluoromethoxy-3-(...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273547(1-(3,4-Bisdifluoromethoxyphenyl)-2-cyclohexylethan...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM39098(2-(1,3-benzothiazol-2-ylmethyl)-1,1-bis(oxidanylid...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273988(1-[3-Methoxy-4-(tetrahydrofuran-3-yloxy)phenyl]but...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336534(CHEMBL1673329 | N'-(6-tert-butylthieno[3,2-d]pyrim...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273986(4-(4-Butyryl-2-methoxyphenoxy)piperidine-1-carboxy...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336533(3-allyl-7-(5-(furan-2-yl)-1,3,4-oxadiazol-2-ylthio...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336530(1-(4-methoxy-3-(tetrahydrofuran-3-yloxy)phenyl)but...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336529(4-(difluoromethoxy)-3-hydroxybenzaldehyde | CHEMBL...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273920(1-[4-Methoxy-3-(tetrahydropyran-4-yloxy)phenyl]pen...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273412(3-Cyclohexyl-1-[4-methoxy-3-(tetrahydrofuran-3-ylo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273507(1-[4-Methoxy-3-(tetrahydrofuran-3-yloxy)phenyl]-3-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336528(CHEMBL1673317 | S-furan-2-ylmethyl 2-(2,3-dihydrob...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336527(CHEMBL1673318 | N-((2-(thiophen-2-yl)thiazol-4-yl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336525(CHEMBL1673320 | ethyl 2-((4-(1,3-dithiolan-2-yl)ph...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336524(CHEMBL1673322 | N-(2-chlorophenyl)-2-(7-chloroquin...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336523(3-benzyl-N-(2-fluorophenyl)-3H-[1,2,3]triazolo[4,5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336522(2-(indolin-1-yl)-N-(5-(thiophen-2-yl)-2,3-dihydro-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336521(2-((4-(1,3-dithiolan-2-yl)phenoxy)methyl)thiazole-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336520(2-(2-(4-chlorophenyl)-2-oxoethylthio)-6-(dimethoxy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336519(3-(4-chlorophenylthio)-1-(pyridin-4-ylmethyl)pyrro...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336518(3-((4-fluorophenylsulfonyl)methyl)-5-(thiophen-2-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336517(1-cyclopentyl-3-(4-(piperidin-1-ylsulfonyl)phenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336516(5-((4-chlorophenylthio)methyl)-3-((pyridin-2-ylsul...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336515((E)-N'-(pyridin-4-ylmethylene)-2-(5-(pyrrolidin-1-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336531(4-methoxy-3-(tetrahydrofuran-3-yloxy)benzaldehyde ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50273335(1-[4-Methoxy-3-(tetrahydrofuran-3-yloxy)phenyl]but...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University Of Georgia

Curated by ChEMBL
LigandPNGBDBM50336532(1-(4-methoxy-3-(tetrahydro-2H-pyran-4-yloxy)phenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Trypanosoma cruzi Y PDEC after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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