Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50039280
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50008923BDBM50008923(4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaz...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326196BDBM50326196((E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-...)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326192BDBM50326192((E)-9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326187BDBM50326187((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-oneO-2-...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326181BDBM50326181((E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326186BDBM50326186((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-one O-2...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326191BDBM50326191((E)-9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326194BDBM50326194((E)-9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326193BDBM50326193((E)-9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326195BDBM50326195((E)-9-methoxy-6-(piperazin-1-yl)-11H-indeno[1,2-c]...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326184BDBM50326184((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-one O-2...)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22984BDBM22984(Adriamycin | (8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326185BDBM50326185((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-oneO-3-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326182BDBM50326182((E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326183BDBM50326183((E)-9-Methoxy-11H-indeno[1,2-c]quinolin-11-oneO-2-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326188BDBM50326188(9-Methoxy-11H-indeno[1,2-c]quinolin-11-one | CHEMB...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326189BDBM50326189((E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetDNA topoisomerase 1(Human)
Kaohsiung Medical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326190BDBM50326190((E)-6-Hydroxy-9-methoxy-11H-indeno[1,2-c]quinolin-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 1 assessed as decrease in pBR322 mobility on agarose gel by electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed