Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50001054
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataKi:  3nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012244(2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataKi:  4.80nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012244(2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataKi:  8.5nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataKi:  12nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50011244(6-{[(4-Benzenesulfonyl-phenyl)-prop-2-ynyl-amino]-...)
Affinity DataKi:  13nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50011244(6-{[(4-Benzenesulfonyl-phenyl)-prop-2-ynyl-amino]-...)
Affinity DataKi:  25nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005203((4-Benzenesulfonyl-benzyl)-(2-imino-1-methyl-1,2-d...)
Affinity DataKi:  31nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005330(5-(4-Benzenesulfonyl-benzyl)-5,6,7,8-tetrahydro-1H...)
Affinity DataKi:  31nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012245(6-{[(4-Benzenesulfonyl-3-trifluoromethyl-phenyl)-p...)
Affinity DataKi:  37nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005330(5-(4-Benzenesulfonyl-benzyl)-5,6,7,8-tetrahydro-1H...)
Affinity DataKi:  43nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012245(6-{[(4-Benzenesulfonyl-3-trifluoromethyl-phenyl)-p...)
Affinity DataKi:  50nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005323(5-[4-(Piperazine-1-sulfonyl)-benzyl]-5,6,7,8-tetra...)
Affinity DataKi:  64nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012240(6-({[4-(Indole-1-sulfonyl)-phenyl]-prop-2-ynyl-ami...)
Affinity DataKi:  69nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005323(5-[4-(Piperazine-1-sulfonyl)-benzyl]-5,6,7,8-tetra...)
Affinity DataKi:  140nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012240(6-({[4-(Indole-1-sulfonyl)-phenyl]-prop-2-ynyl-ami...)
Affinity DataKi:  150nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012243(2-Methyl-6-{[prop-2-ynyl-(3-trifluoromethyl-phenyl...)
Affinity DataKi:  390nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012243(2-Methyl-6-{[prop-2-ynyl-(3-trifluoromethyl-phenyl...)
Affinity DataKi:  450nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005202(6-[(4-Benzenesulfonyl-benzyl)-methyl-amino]-1-meth...)
Affinity DataKi:  770nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005183(1-Methyl-6-{methyl-[4-(piperazine-1-sulfonyl)-benz...)
Affinity DataKi:  840nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005202(6-[(4-Benzenesulfonyl-benzyl)-methyl-amino]-1-meth...)
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005203((4-Benzenesulfonyl-benzyl)-(2-imino-1-methyl-1,2-d...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012242(2-Methyl-6-[(phenyl-prop-2-ynyl-amino)-methyl]-3H-...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012241(4-(4-{[Ethyl-(2-oxo-1,2-dihydro-benzo[cd]indol-6-y...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012242(2-Methyl-6-[(phenyl-prop-2-ynyl-amino)-methyl]-3H-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005328(5-[4-(Piperazine-1-sulfonyl)-benzyl]-5,6,7,8-tetra...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005328(5-[4-(Piperazine-1-sulfonyl)-benzyl]-5,6,7,8-tetra...)
Affinity DataKi:  7.70E+3nMAssay Description:Inhibition of human Thymidylate synthase (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50005183(1-Methyl-6-{methyl-[4-(piperazine-1-sulfonyl)-benz...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Agouron Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012241(4-(4-{[Ethyl-(2-oxo-1,2-dihydro-benzo[cd]indol-6-y...)
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of Thymidylate synthase of E. coli (Ki)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed