Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50032169
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325328BDBM50325328(4-((1H-imidazol-1-yl)methyl)phenyl biphenyl-4-sulf...)
Affinity DataIC50: 10nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296971BDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50: 14nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325329BDBM50325329(4-((1H-imidazol-1-yl)methyl)phenyl 4-ethylbenzenes...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325330BDBM50325330(4-((1H-imidazol-1-yl)methyl)phenyl 4-propylbenzene...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296969BDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50: 30nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296976BDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50: 34nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296969BDBM50296969(4-((1H-imidazol-1-yl)methyl)phenyl 4-methylbenzene...)
Affinity DataIC50: 40nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325331BDBM50325331(4-((1H-imidazol-1-yl)methyl)phenyl 4-butylbenzenes...)
Affinity DataIC50: 40nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325331BDBM50325331(4-((1H-imidazol-1-yl)methyl)phenyl 4-butylbenzenes...)
Affinity DataIC50: 70nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325328BDBM50325328(4-((1H-imidazol-1-yl)methyl)phenyl biphenyl-4-sulf...)
Affinity DataIC50: 100nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325329BDBM50325329(4-((1H-imidazol-1-yl)methyl)phenyl 4-ethylbenzenes...)
Affinity DataIC50: 110nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325332BDBM50325332(4-((1H-imidazol-1-yl)methyl)phenyl 4-pentylbenzene...)
Affinity DataIC50: 130nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325332BDBM50325332(4-((1H-imidazol-1-yl)methyl)phenyl 4-pentylbenzene...)
Affinity DataIC50: 160nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188092BDBM50188092(4-iodobenzyl imidazole | 1-(4-iodobenzyl)-1H-imida...)
Affinity DataIC50: 164nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296971BDBM50296971(4-((1H-imidazol-1-yl)methyl)phenyl 4-fluorobenzene...)
Affinity DataIC50: 200nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31768BDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 206nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188092BDBM50188092(4-iodobenzyl imidazole | 1-(4-iodobenzyl)-1H-imida...)
Affinity DataIC50: 730nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50296976BDBM50296976(4-((1H-imidazol-1-yl)methyl)phenyl 4-(trifluoromet...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325330BDBM50325330(4-((1H-imidazol-1-yl)methyl)phenyl 4-propylbenzene...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188086BDBM50188086(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50188086BDBM50188086(4-((1H-imidazol-1-yl)methyl)phenol | 4-Imidazol-1-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31768BDBM31768(Nizoral | CHEMBL295698 | Panfungol | Ketoconazole)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7887BDBM7887(1-benzylimidazole | 1-Benzylimidazole (BI) | CHEMB...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 17-alpha-hydroxylase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
University of The West of Scotland

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7887BDBM7887(1-benzylimidazole | 1-Benzylimidazole (BI) | CHEMB...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of 17,20-lyase activity of rat testicular microsomal P450-17alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed