Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50032181
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325632BDBM50325632((7-fluoro-1H-indol-5-yl)(2-propylpyrrolidin-2-yl)m...)
Affinity DataIC50: 30nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325619BDBM50325619((7-fluoro-1H-indol-5-yl)(3-isopentylpyrrolidin-3-y...)
Affinity DataIC50: 50nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325614BDBM50325614((3-benzylpyrrolidin-3-yl)(7-fluoro-1H-indol-5-yl)m...)
Affinity DataIC50: 70nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325614BDBM50325614((3-benzylpyrrolidin-3-yl)(7-fluoro-1H-indol-5-yl)m...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325614BDBM50325614((3-benzylpyrrolidin-3-yl)(7-fluoro-1H-indol-5-yl)m...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325631BDBM50325631((1H-indol-5-yl)(2-propylpyrrolidin-2-yl)methanone ...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325639BDBM50325639((3-(3,3-dimethylbutyl)pyrrolidin-3-yl)(quinolin-2-...)
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325618BDBM50325618((3-butyl pyrrolidin-3-yl)(7-fluoro-1H-indol-5-yl)m...)
Affinity DataIC50: 750nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325618BDBM50325618((3-butyl pyrrolidin-3-yl)(7-fluoro-1H-indol-5-yl)m...)
Affinity DataIC50: 750nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325616BDBM50325616((7-fluoro-1H-indol-5-yl)(3-isobutyl pyrrolidin-3-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325616BDBM50325616((7-fluoro-1H-indol-5-yl)(3-isobutyl pyrrolidin-3-y...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325620BDBM50325620((3-(3,3-dimethylbutyl)pyrrolidin-3-yl)(7-fluoro-1H...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325620BDBM50325620((3-(3,3-dimethylbutyl)pyrrolidin-3-yl)(7-fluoro-1H...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325615BDBM50325615((7-fluoro-1H-indol-5-yl)(3-propylpyrrolidin-3-yl)m...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325615BDBM50325615((7-fluoro-1H-indol-5-yl)(3-propylpyrrolidin-3-yl)m...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325625BDBM50325625((5,6-dichloropyridin-2-yl)(3-(3,3-dimethylbutyl)py...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325633BDBM50325633((3,4-dichloro phenyl)(2-propylpyrrolidin-2-yl)meth...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325633BDBM50325633((3,4-dichloro phenyl)(2-propylpyrrolidin-2-yl)meth...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325633BDBM50325633((3,4-dichloro phenyl)(2-propylpyrrolidin-2-yl)meth...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325626BDBM50325626((4-amino-3-chlorophenyl)(3-(3,3-dimethylbutyl)pyrr...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325617BDBM50325617((3-(ethoxymethyl)pyrrolidin-3-yl)(7-fluoro-1H-indo...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325632BDBM50325632((7-fluoro-1H-indol-5-yl)(2-propylpyrrolidin-2-yl)m...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325637BDBM50325637((1H-indazol-5-yl)(2-isobutylpyrrolidin-2-yl)methan...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325634BDBM50325634((4-amino-3-chlorophenyl)(2-propylpyrrolidin-2-yl)m...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325622BDBM50325622((3,4-dichlorophenyl)(3-(3,3-dimethylbutyl)pyrrolid...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325622BDBM50325622((3,4-dichlorophenyl)(3-(3,3-dimethylbutyl)pyrrolid...)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325638BDBM50325638((2-(3,3-dimethylbutyl)pyrrolidin-2-yl)(1H-indazol-...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325640BDBM50325640((3-(3,3-dimethylbutyl)pyrrolidin-3-yl)(5-methylqui...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325631BDBM50325631((1H-indol-5-yl)(2-propylpyrrolidin-2-yl)methanone ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325637BDBM50325637((1H-indazol-5-yl)(2-isobutylpyrrolidin-2-yl)methan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325636BDBM50325636((1H-indazol-5-yl)(2-propylpyrrolidin-2-yl)methanon...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325635BDBM50325635((4-amino-3-chlorophenyl)(2-(isopropoxymethyl)pyrro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325634BDBM50325634((4-amino-3-chlorophenyl)(2-propylpyrrolidin-2-yl)m...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325638BDBM50325638((2-(3,3-dimethylbutyl)pyrrolidin-2-yl)(1H-indazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325642BDBM50325642((4-amino-3-chlorophenyl)(2-isobutylpyrrolidin-2-yl...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325641BDBM50325641((S)-(3,4-dichlorophenyl)(2-propylpyrrolidin-2-yl)m...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325629BDBM50325629(benzo[b]thiophen-2-yl(3-(3,3-dimethylbutyl)pyrroli...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325621BDBM50325621((3-chloro-4-methylphenyl)(3-(3,3-dimethylbutyl)pyr...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325623BDBM50325623((3,4-dichloro-5-fluorophenyl)(3-(3,3-dimethylbutyl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325635BDBM50325635((4-amino-3-chlorophenyl)(2-(isopropoxymethyl)pyrro...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325628BDBM50325628((3-(3,3-dimethylbutyl)pyrrolidin-3-yl)(1H-indazol-...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325636BDBM50325636((1H-indazol-5-yl)(2-propylpyrrolidin-2-yl)methanon...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325624BDBM50325624((4,5-dichlorothiophen-2-yl)(3-(3,3-dimethylbutyl)p...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325630BDBM50325630((3-(3,3-dimethylbutyl)pyrrolidin-3-yl)(1H-indol-2-...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Roche Palo Alto

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325627BDBM50325627((6-amino-5-chloropyridin-3-yl)(3-(3,3-dimethylbuty...)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/20/2011
Entry Details Article
PubMed