Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50022553
Affinity DataKi: 0.240nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 (781 to 1124 residues) expressed in insect cells using FITC-KGGEEEEYFE as substrate in presence of va...More data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Competitive inhibition of recombinant human GST-fused JAK1 (852 to 1142 residues) using 5-FAM-KKSRGDYMTMQIG as substrate in presence of varying level...More data for this Ligand-Target Pair
Affinity DataKi: 0.990nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 (809 to 1153+9 residues) expressed in insect cells using FITC-KGGEEEEYFE as substrate in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human GST-tagged JAK3 (781 to 1124 residues) expressed in insect cells using FITC-KGGEEEEYFE as substrate in presence of Mg...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human GST-fused JAK1 (852 to 1142 residues) using 5-FAM-KKSRGDYMTMQIG as substrate in presence of MgATP by caliper mobility...More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant human GST-tagged JAK2 (809 to 1153+9 residues) expressed in insect cells using FITC-KGGEEEEYFE as substrate in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-21-induced STAT3 phosphorylation in CD3+ T cells preincubated for 1 hr follo...More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-2-induced STAT5 phosphorylation in CD3+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-7-induced STAT5 phosphorylation in CD3+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of JAK1/JAK3 in mouse whole blood assessed as reduction in IL-15-induced STAT5 phosphorylation in CD8+ T cells preincubated for 1 hr follo...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFN-alpha-induced STAT1 phosphorylation in CD3+ T cells preincubated for 1 hr f...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-4-induced STAT6 phosphorylation in CD3+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of JAK1/JAK2 in human whole blood assessed as reduction in IL-6-induced STAT1 phosphorylation in CD3+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as reduction in IL-15-induced STAT5 phosphorylation in CD8+ T cells preincubated for 1 hr follo...More data for this Ligand-Target Pair
Affinity DataIC50: 148nMAssay Description:Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFN-alpha-induced STAT1 phosphorylation in monocytes preincubated for 1 hr foll...More data for this Ligand-Target Pair
Affinity DataIC50: 178nMAssay Description:Inhibition of JAK1/JAK2 in human whole blood assessed as reduction in IFN-gamma-induced STAT1 phosphorylation in monocytes preincubated for 1 hr foll...More data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Inhibition of JAK1/JAK2 in mouse whole blood assessed as reduction in IL-6-induced STAT1 phosphorylation in CD8+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataIC50: 324nMAssay Description:Inhibition of JAK2 in human HUO3 cells assessed as reduction in GM-CSF-induced cell proliferation measured after 4 days by [3H]-thymidine incorporati...More data for this Ligand-Target Pair
Affinity DataIC50: 367nMAssay Description:Inhibition of JAK1/JAK2 in human whole blood assessed as reduction in IL-6-induced STAT3 phosphorylation in CD3+ T cells preincubated for 1 hr follow...More data for this Ligand-Target Pair
Affinity DataIC50: 406nMAssay Description:Inhibition of JAK1/JAK2 in human whole blood assessed as reduction in IL-6-induced STAT3 phosphorylation in monocytes preincubated for 1 hr followed ...More data for this Ligand-Target Pair
Affinity DataIC50: 877nMAssay Description:Inhibition of JAK2 in rat whole blood assessed as reduction in GM-CSF-induced STAT5 phosphorylation in monocytes preincubated for 1 hr followed by IL...More data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of JAK2 in human whole blood assessed as reduction in GM-CSF-induced STAT5 phosphorylation in monocytes preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
Affinity DataIC50: 4.38E+3nMAssay Description:Inhibition of JAK2 in mouse whole blood assessed as reduction in GM-CSF-induced STAT5 phosphorylation in monocytes preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
