Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50032305
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326904BDBM50326904(8-(2,4-Difluorophenyl)-3-(2,4-difluorophenylamino)...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326917BDBM50326917(N-Cyclopropyl-3-(8-(2,4-difluorophenyl)-1-methyl-2...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326925BDBM50326925(3-(8-(2-Chloro-5-fluorophenyl)-1-methyl-2-oxo-1,2-...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326921BDBM50326921(3-(8-(2-Chlorophenyl)-1-methyl-2-oxo-1,2-dihydropy...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326903BDBM50326903(8-(2,4-Difluorophenyl)-3-(4-fluorophenylamino)-1-m...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326918BDBM50326918(4-Chloro-N-cyclopropyl-3-(8-(2,4-difluorophenyl)-1...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326920BDBM50326920(N-Cyclopropyl-4-methyl-3-(1-methyl-2-oxo-8-o-tolyl...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326913BDBM50326913(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326914BDBM50326914(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326915BDBM50326915(N-Cyclopropyl-3-(8-(2,4-difluorophenyl)-1-methyl-2...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326924BDBM50326924(N-Cyclopropyl-3-(8-(2-fluoro-4-(trifluoromethyl)ph...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326923BDBM50326923(N-Cyclopropyl-3-(8-(4-fluoro-2-methylphenyl)-1-met...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326916BDBM50326916(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326922BDBM50326922(N-Cyclopropyl-4-methyl-3-(1-methyl-2-oxo-8-(2-(tri...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326911BDBM50326911(3-(2,4-Difluorobenzyl)-8-(2,4-difluorophenyl)-1-me...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326909BDBM50326909(3-(2,4-Difluorophenoxy)-8-(2,4-difluorophenyl)-1-m...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326919BDBM50326919(N-Cyclopropyl-4-(8-(2,4-difluorophenyl)-1-methyl-2...)
Affinity DataIC50: 14.5nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326910BDBM50326910(3-(4-Fluorobenzyl)-8-(2,4-difluorophenyl)-1-methyl...)
Affinity DataIC50: 55.8nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326908BDBM50326908(8-(2,4-Difluorophenyl)-3-(4-fluorophenoxy)-1-methy...)
Affinity DataIC50: 78nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326906BDBM50326906(8-(2,4-Difluorophenyl)-3-(3,5-difluoropyridin-2-yl...)
Affinity DataIC50: 111nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326907BDBM50326907(8-(2,4-Difluorophenyl)-3-((4-fluorophenyl)(methyl)...)
Affinity DataIC50: 299nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326905BDBM50326905(8-(2,4-Difluorophenyl)-3-(5-fluoropyridin-2-ylamin...)
Affinity DataIC50: 328nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326912BDBM50326912(3-(8-(2,4-Difluorophenyl)-1-methyl-2-oxo-1,2-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of p38alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed