Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 5722
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM50293744(KSP Inhibitor, 4e | CHEMBL563643 | 2-(4-sulfamoylp...)
Affinity DataKd:  600nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM50293759(CHEMBL563846 | KSP Inhibitor, 4f | 2-(4-methoxyphe...)
Affinity DataKd:  1.20E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM50293756(KSP Inhibitor, 4a | CHEMBL561696 | 2-(4-(methylthi...)
Affinity DataKd:  2.00E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM50293753(KSP Inhibitor, 4b | CHEMBL565195 | 2-(4-(methylsul...)
Affinity DataKd:  2.50E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM92866(KSP Inhibitor, 4g)
Affinity DataKd:  3.40E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM92865(KSP Inhibitor, 4d)
Affinity DataKd:  5.00E+3nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetKinesin-like protein KIF11(Human)
Merck Research Laboratories

LigandPNGBDBM92864(KSP Inhibitor, 4c)
Affinity DataKd:  1.40E+4nMAssay Description:Binding assay using temperature-dependent circular dichroism (TdCD). In TdCD, the loss of protein secondary structure was monitored as a function of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed