Compile Data Set for Download or QSAR
maximum 50k data
Found 68 Enz. Inhib. hit(s) with all data for entry = 50032563
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331074((S)-8-methyl-6-(trifluoromethoxy)-2-(trifluorometh...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331065(8-methyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331063(8-chloro-6-ethynyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331052(6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chrome...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331071((S)-6-chloro-7,8-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331057(2,6-bis(trifluoromethyl)-2H-chromene-3-carboxylic ...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331078((S)-8-propyl-6-(trifluoromethoxy)-2-(trifluorometh...)
Affinity DataIC50:  42nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331078((S)-8-propyl-6-(trifluoromethoxy)-2-(trifluorometh...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331069((S)-6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331076((S)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethy...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331054(6-ethynyl-2-(trifluoromethyl)-2H-chromene-3-carbox...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331076((S)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethy...)
Affinity DataIC50:  74nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331058(6-chloro-8-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  84nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331056(6-cyano-2-(trifluoromethyl)-2H-chromene-3-carboxyl...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331067(6-chloro-7,8-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331055(6-ethyl-2-(trifluoromethyl)-2H-chromene-3-carboxyl...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331066(6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331063(8-chloro-6-ethynyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331064(6-ethyl-8-methyl-2-(trifluoromethyl)-2H-chromene-3...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331065(8-methyl-6-(trifluoromethoxy)-2-(trifluoromethyl)-...)
Affinity DataIC50:  140nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331059(8-chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331068(6-chloro-5,8-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331060(6,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3-car...)
Affinity DataIC50: <240nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331061(8-chloro-6-methoxy-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  240nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331050(6-methyl-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331064(6-ethyl-8-methyl-2-(trifluoromethyl)-2H-chromene-3...)
Affinity DataIC50:  270nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331073((S)-6,8-dimethyl-2-(trifluoromethyl)-2H-chromene-3...)
Affinity DataIC50:  290nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331049(6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331080(8-methoxy-6-(trifluoromethoxy)-2-(trifluoromethyl)...)
Affinity DataIC50:  320nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331055(6-ethyl-2-(trifluoromethyl)-2H-chromene-3-carboxyl...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331058(6-chloro-8-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  470nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331076((S)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethy...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331080(8-methoxy-6-(trifluoromethoxy)-2-(trifluoromethyl)...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331051(6-formyl-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50:  730nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331077((R)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethy...)
Affinity DataIC50:  860nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331059(8-chloro-6-methyl-2-(trifluoromethyl)-2H-chromene-...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331070((R)-6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331079((R)-8-propyl-6-(trifluoromethoxy)-2-(trifluorometh...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331069((S)-6-chloro-5,7-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331068(6-chloro-5,8-dimethyl-2-(trifluoromethyl)-2H-chrom...)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331074((S)-8-methyl-6-(trifluoromethoxy)-2-(trifluorometh...)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331062(8-methoxy-6-methyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  3.33E+3nMAssay Description:Inhibition of human COX-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331057(2,6-bis(trifluoromethyl)-2H-chromene-3-carboxylic ...)
Affinity DataIC50:  4.39E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331071((S)-6-chloro-7,8-dimethyl-2-(trifluoromethyl)-2H-c...)
Affinity DataIC50:  4.99E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331078((S)-8-propyl-6-(trifluoromethoxy)-2-(trifluorometh...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331062(8-methoxy-6-methyl-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  9.62E+3nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331052(6-(trifluoromethoxy)-2-(trifluoromethyl)-2H-chrome...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331076((S)-8-ethyl-6-(trifluoromethoxy)-2-(trifluoromethy...)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331061(8-chloro-6-methoxy-2-(trifluoromethyl)-2H-chromene...)
Affinity DataIC50:  2.56E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50331049(6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxy...)
Affinity DataIC50:  2.92E+4nMAssay Description:Inhibition of human COX-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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