Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50032306
TargetATP-dependent translocase ABCB1(Human)
Umr 5086 Cnrs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326928BDBM50326928((2S,4R)-tert-butyl 4-(benzyloxy)-2-(((S)-6-(benzyl...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Umr 5086 Cnrs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326930BDBM50326930((2S,4R)-tert-butyl 4-(benzyloxy)-2-((S)-6-(benzylo...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Umr 5086 Cnrs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326931BDBM50326931((2S,4R)-tert-butyl 2-((S)-6-(benzyloxycarbonylamin...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Umr 5086 Cnrs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326927BDBM50326927((S)-tert-butyl 2-((S)-4-(benzyloxy)-2-(tert-butoxy...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Umr 5086 Cnrs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326926BDBM50326926((5S)-tert-butyl 5-(tert-butoxycarbonylamino)-6-(4-...)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
Umr 5086 Cnrs

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50326929BDBM50326929((2S,4R)-tert-butyl 2-((S)-6-(benzyloxycarbonylamin...)
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of human MDR1 expressed in mouse NIH3T3 cells assessed as inhibition of drug efflux by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed