Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50032378
LigandPNGBDBM50328080(3-(6-(1H-indazol-4-yl)-1-methyl-1H-pyrazolo[3,4-d]...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328082(6-(1H-indazol-4-yl)-1-methyl-N-(4-(methylsulfonyl)...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328076(6-(1H-indazol-4-yl)-N-(3-methoxyphenyl)-1-methyl-1...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328079(6-(1H-indazol-4-yl)-1-methyl-N-(3-(methylsulfonyl)...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328078(N-(3-methoxyphenyl)-1-methyl-6-(3-methylbenzo[d]is...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328083(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328084(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328081(6-(1H-indazol-4-yl)-1-methyl-N-(1-methylpiperidin-...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328077(6-(3-amino-1H-indazol-4-yl)-N-(3-methoxyphenyl)-1-...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328075(6-(2-aminopyrimidin-5-yl)-N-(3-methoxyphenyl)-1-me...)
Affinity DataIC50: 16nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328074(N-(3-methoxyphenyl)-1-methyl-6-(pyridin-3-yl)-1H-p...)
Affinity DataIC50: 29nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 31nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328070(N-(3-methoxyphenyl)-1-methyl-6-(3-(methylsulfonyl)...)
Affinity DataIC50: 56nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328071(3-(4-(3-methoxyphenylamino)-1-methyl-1H-pyrazolo[3...)
Affinity DataIC50: 72nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328067(6-(1,1-dioxidothiomorpholin-4-yl)-N-(3-methoxyphen...)
Affinity DataIC50: 75nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328069(N,6-bis(3-methoxyphenyl)-1-methyl-1H-pyrazolo[3,4-...)
Affinity DataIC50: 134nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328064(CHEMBL1258354 | ETP-7382 | N-(3-methoxyphenyl)-1-m...)
Affinity DataIC50: 162nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 187nMAssay Description:Inhibition of PI3Kalpha in human PC3 cells assessed as phosphorylated Akt levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328068(N-(3-methoxyphenyl)-1-methyl-6-(piperidin-1-yl)-1H...)
Affinity DataIC50: 359nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328066(6-(2,6-dimethylmorpholino)-N-(3-methoxyphenyl)-1-m...)
Affinity DataIC50: 370nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328073(N-(3-(4-(3-methoxyphenylamino)-1-methyl-1H-pyrazol...)
Affinity DataIC50: 386nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328065(1-(4-(3-methoxyphenylamino)-1-methyl-1H-pyrazolo[3...)
Affinity DataIC50: 430nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
LigandPNGBDBM50328072(3-(4-(3-methoxyphenylamino)-1-methyl-1H-pyrazolo[3...)
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50328085(6-(1H-indazol-4-yl)-1-methyl-4-(4-(methylsulfonyl)...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed