BindingDB PrimarySearch_ki

Found 26 Enz. Inhib. hit(s) with all data for entry = 50032659

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)

Ki: 2nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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MCE
KEGG PC cid PC sid PDB Similars

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3D Structure (crystal)

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)

Ki: 20nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

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Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50155639(Acetaldehyde O-((S)-1-methyl-pyrrolidin-2-ylmethyl...)

Ki: 330nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332839(CHEMBL1630288 | anti(2S,5'S)-(+)-5b3-Methyl-5-pyrr...)

Ki: 440nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)

Ki: 469nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase ChEBI
MCE
KEGG PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)

Ki: 520nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50035398((S)-1-Methyl-2-(3-methyl-isoxazol-5-yl)-pyrrolidin...)

Ki: 1.20E+3nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL PC cid PC sid Patents Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332836(CHEMBL1630294 | syn(2S,5'R)-(-)-3-Methoxy-5-(1-met...)

Ki: 2.90E+3nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332842(CHEMBL1630291 | syn(2S,5'R)-(-)-3-Bromo-5-(1-methy...)

Ki: 3.80E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332841(CHEMBL1630290 | syn(2S,5'R)-(-)-3-Bromo-5-pyrrolid...)

Ki: 4.20E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332839(CHEMBL1630288 | anti(2S,5'S)-(+)-5b3-Methyl-5-pyrr...)

Ki: 5.10E+3nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332836(CHEMBL1630294 | syn(2S,5'R)-(-)-3-Methoxy-5-(1-met...)

Ki: 1.03E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332835(CHEMBL1630293 | anti(2S,5'S)-(+)-3-Methoxy-5-pyrro...)

Ki: 1.13E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332840(CHEMBL1630289 | syn(2S,5'R)-(-)-3-Methyl-5-(1-meth...)

Ki: 1.20E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332838(CHEMBL1630287 | syn(2S,5'R)-(-)-3-Methyl-5-pyrroli...)

Ki: 1.80E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332834(CHEMBL1630292 | syn(2S,5'R)-(-)-3-Methoxy-5-pyrrol...)

Ki: 2.80E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332841(CHEMBL1630290 | syn(2S,5'R)-(-)-3-Bromo-5-pyrrolid...)

Ki: 3.50E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332838(CHEMBL1630287 | syn(2S,5'R)-(-)-3-Methyl-5-pyrroli...)

Ki: 4.00E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332842(CHEMBL1630291 | syn(2S,5'R)-(-)-3-Bromo-5-(1-methy...)

Ki: 4.30E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50155637(CHEMBL186295 | Propan-2-one O-((S)-1-methyl-pyrrol...)

Ki: 4.90E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332835(CHEMBL1630293 | anti(2S,5'S)-(+)-3-Methoxy-5-pyrro...)

Ki: 5.00E+4nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50155639(Acetaldehyde O-((S)-1-methyl-pyrrolidin-2-ylmethyl...)

Ki: >5.00E+4nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332837(CHEMBL1630295 | anti(2S,5'S)-(+)-3-tert-butoxy-5-p...)

Ki: 1.84E+5nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR in rat cortical membranes by beta countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332834(CHEMBL1630292 | syn(2S,5'R)-(-)-3-Methoxy-5-pyrrol...)

Ki: 2.77E+5nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332840(CHEMBL1630289 | syn(2S,5'R)-(-)-3-Methyl-5-(1-meth...)

Ki: 3.25E+5nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL

PNG

BDBM50332837(CHEMBL1630295 | anti(2S,5'S)-(+)-3-tert-butoxy-5-p...)

Ki: >5.00E+5nMAssay Description:Displacement of [125I]-alpha-Bungarotoxin from alpha7 nAChR rat cortical membranes by gamma countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed