Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) with all data for entry = 50032536
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330764(2-(4-Trifluoromethylphenyl)-4(5)-phenylimidazole |...)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330765(2-Phenyl-4(5)-(3-chlorophenyl)imidazole | 4-(3-chl...)
Affinity DataIC50:  1.79E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50330763(2-(4-Methoxyphenyl)-4(5)-phenylimidazole | 2-(4-me...)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50133778(2,4(5)-Diphenylimidazole | 2,4-diphenyl-1H-imidazo...)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50003655(Phenytoin)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human NaV1.2 expressed in HEK cells at -60 mV holding potential by patch clamp recording techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed