Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50032575
LigandPNGBDBM50331290(CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...)
Affinity DataIC50:  160nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331290(CHEMBL1289953 | N-(3-aminopropyl)-2-(3-methylbenzy...)
Affinity DataIC50:  190nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82302(5-BENZYLOXYTRYPTAMINE | 5-BZT | CAS_20776-45-8 | C...)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331285(2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...)
Affinity DataIC50:  1.50E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331285(2-(5-(benzyloxy)-2-methyl-1H-indol-3-yl)ethanamine...)
Affinity DataIC50:  2.36E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  3.34E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054758(CHEMBL357130 | [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...)
Affinity DataIC50:  5.63E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50054758(CHEMBL357130 | [2-(5-Benzyloxy-1H-indol-3-yl)-ethy...)
Affinity DataIC50:  5.96E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50247069(2-(7-(benzyloxy)-1H-indol-3-yl)ethanamine | CHEMBL...)
Affinity DataIC50:  8.93E+3nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataIC50:  1.16E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30853(2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochlor...)
Affinity DataIC50:  1.23E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM82087(2-(5-methoxy-1H-indol-3-yl)ethanamine | 5-MT | 5-M...)
Affinity DataIC50:  1.24E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM30853(2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochlor...)
Affinity DataIC50:  1.31E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331286(2-(5-chloro-1H-indol-3-yl)ethanamine | 5-Cl-T | CH...)
Affinity DataIC50:  2.15E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331287(CHEMBL1289952 | ethyl 2-(5-(benzyloxy)-1H-indol-3-...)
Affinity DataIC50:  2.16E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331288(2-(5-bromo-1H-indol-3-yl)ethanamine | 5-Br-T | CHE...)
Affinity DataIC50:  2.27E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of menthol-induced 45calcium influx treated 5 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331287(CHEMBL1289952 | ethyl 2-(5-(benzyloxy)-1H-indol-3-...)
Affinity DataIC50:  2.88E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331288(2-(5-bromo-1H-indol-3-yl)ethanamine | 5-Br-T | CHE...)
Affinity DataIC50:  3.04E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50331286(2-(5-chloro-1H-indol-3-yl)ethanamine | 5-Cl-T | CH...)
Affinity DataIC50:  3.22E+4nMAssay Description:Antagonist activity at human TRPM8 receptor expressed in human T-REx-293 cells assessed as inhibition of icilin-induced 45calcium influx treated 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed