Compile Data Set for Download or QSAR
Report error Found 126 Enz. Inhib. hit(s) with all data for entry = 50032670
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332966BDBM50332966(7,8-dichloro-4-(3-(2-methylpyridin-4-yl)phenyl)-1H...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332962BDBM50332962(7-methyl-4-(3-(pyridin-3-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332963BDBM50332963(4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-...)
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332964BDBM50332964(4-(3-(2-ethyl-6-methylpyridin-4-yl)phenyl)-7-methy...)
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332965BDBM50332965(4-(3-(2-cyclopropyl-6-methylpyridin-4-yl)phenyl)-7...)
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332968BDBM50332968(7-ethoxy-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(tri...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at rat mGluR3 receptor expressed in CHO cells assessed as inhibition of GIRK currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332962BDBM50332962(7-methyl-4-(3-(pyridin-3-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332963BDBM50332963(4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332967BDBM50332967(8-chloro-4-(3-(pyridin-4-yl)phenyl)-1H-benzo[b][1,...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332969BDBM50332969(7-methyl-4-(3-(pyridin-4-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332970BDBM50332970(7-methyl-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(tri...)
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332971BDBM50332971(4-(3-(2-isopropylpyridin-4-yl)phenyl)-7-methyl-8-(...)
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332965BDBM50332965(4-(3-(2-cyclopropyl-6-methylpyridin-4-yl)phenyl)-7...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332972BDBM50332972(7-ethoxy-4-(3-(pyridin-4-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332966BDBM50332966(7,8-dichloro-4-(3-(2-methylpyridin-4-yl)phenyl)-1H...)
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332970BDBM50332970(7-methyl-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(tri...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332964BDBM50332964(4-(3-(2-ethyl-6-methylpyridin-4-yl)phenyl)-7-methy...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332976BDBM50332976(4-(3-(2-benzylpyridin-4-yl)phenyl)-7-methyl-8-(tri...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332977BDBM50332977(7-methyl-4-(3-(6-methylpyridin-3-yl)phenyl)-8-(tri...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332978BDBM50332978(4-(3-(2-(methoxymethyl)-6-methylpyridin-4-yl)pheny...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332973BDBM50332973(7-methyl-4-(3-(3-methylisoxazol-5-yl)phenyl)-8-(tr...)
Affinity DataIC50: 5nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332974BDBM50332974(4-(3-(6-methoxypyridin-3-yl)phenyl)-7-methyl-8-(tr...)
Affinity DataIC50: 5nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332975BDBM50332975(4-(3-(2-ethylpyridin-4-yl)phenyl)-7-methyl-8-(trif...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332980BDBM50332980(7-methyl-4-(3-(pyrimidin-4-yl)phenyl)-8-(trifluoro...)
Affinity DataIC50: 6nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332968BDBM50332968(7-ethoxy-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(tri...)
Affinity DataIC50: 6nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332981BDBM50332981(4-(3-(2-cyclopropylpyridin-4-yl)phenyl)-7-methyl-8...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332982BDBM50332982(4-(3-(2-(methoxymethyl)pyridin-4-yl)phenyl)-7-meth...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332979BDBM50332979(4-(3-(6-cyclopropylpyridin-3-yl)phenyl)-7-methyl-8...)
Affinity DataIC50: 6nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332972BDBM50332972(7-ethoxy-4-(3-(pyridin-4-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat mGluR3 receptor expressed in CHO cells assessed as inhibition of GIRK currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332966BDBM50332966(7,8-dichloro-4-(3-(2-methylpyridin-4-yl)phenyl)-1H...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at human mGluR2 receptor expressed in CHO cells assessed as inhibition of GIRK currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332983BDBM50332983(4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7,8-bis(tri...)
Affinity DataIC50: 7nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332984BDBM50332984(4-(3-(2-cyclopentylpyridin-4-yl)phenyl)-7-methyl-8...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332983BDBM50332983(4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7,8-bis(tri...)
Affinity DataIC50: 7nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332967BDBM50332967(8-chloro-4-(3-(pyridin-4-yl)phenyl)-1H-benzo[b][1,...)
Affinity DataIC50: 8nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332972BDBM50332972(7-ethoxy-4-(3-(pyridin-4-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at rat mGluR2 receptor expressed in CHO cells assessed as inhibition of GIRK currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332985BDBM50332985(4-(3-(1H-1,2,4-triazol-1-yl)phenyl)-7-methyl-8-(tr...)
Affinity DataIC50: 8nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332975BDBM50332975(4-(3-(2-ethylpyridin-4-yl)phenyl)-7-methyl-8-(trif...)
Affinity DataIC50: 8nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332978BDBM50332978(4-(3-(2-(methoxymethyl)-6-methylpyridin-4-yl)pheny...)
Affinity DataIC50: 8nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332968BDBM50332968(7-ethoxy-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(tri...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332973BDBM50332973(7-methyl-4-(3-(3-methylisoxazol-5-yl)phenyl)-8-(tr...)
Affinity DataIC50: 9nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332986BDBM50332986(4-(3-(1H-1,2,3-triazol-1-yl)phenyl)-7-methyl-8-(tr...)
Affinity DataIC50: 9nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332987BDBM50332987(4-(3-(6-ethylpyridin-3-yl)phenyl)-7-methyl-8-(trif...)
Affinity DataIC50: 9nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332981BDBM50332981(4-(3-(2-cyclopropylpyridin-4-yl)phenyl)-7-methyl-8...)
Affinity DataIC50: 10nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332984BDBM50332984(4-(3-(2-cyclopentylpyridin-4-yl)phenyl)-7-methyl-8...)
Affinity DataIC50: 10nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332988BDBM50332988(4-(3-(6-isopropylpyridin-3-yl)phenyl)-7-methyl-8-(...)
Affinity DataIC50: 10nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332972BDBM50332972(7-ethoxy-4-(3-(pyridin-4-yl)phenyl)-8-(trifluorome...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332967BDBM50332967(8-chloro-4-(3-(pyridin-4-yl)phenyl)-1H-benzo[b][1,...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human mGluR2 receptor expressed in CHO cells assessed as inhibition of GIRK currentMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332989BDBM50332989(4-(3-(pyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-...)
Affinity DataIC50: 10nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332971BDBM50332971(4-(3-(2-isopropylpyridin-4-yl)phenyl)-7-methyl-8-(...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50332988BDBM50332988(4-(3-(6-isopropylpyridin-3-yl)phenyl)-7-methyl-8-(...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2011
Entry Details Article
PubMed
Displayed 1 to 50 (of 126 total ) | Next | Last >>
Jump to: