Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50033312
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343152(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataKi:  0.0910nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343153(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataKi:  0.276nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataKi:  0.305nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343154(2-(3-((R)-2-((R)-2-(3,5-dihydroxyphenyl)-2-hydroxy...)
Affinity DataKi:  0.397nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343157(N-(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-p...)
Affinity DataKi:  0.634nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343158(2-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-(4-(...)
Affinity DataKi:  0.765nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343160(N-(5-((R)-2-(6-(4-(3-((R)-3-(diisopropylamino)-1-p...)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50326547(N-(3,4-dichlorobenzyl)-2-(3-((R)-2-((R)-2-hydroxy-...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343156(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343153(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at adrenergic beta2 receptor in guinea pig trachea assessed as bronchorelaxation activity against histamine-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50165008(2-[(1R)-3-(diisopropylamino)-1-phenylpropyl]-4-met...)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at adrenergic beta2 receptor in guinea pig trachea assessed as bronchorelaxation activity against histamine-induced contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343161(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at muscarinic M3 receptor in guinea pig trachea assessed as bronchorelaxation activity in presence of propranololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343159(4-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataKi:  4.70nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor(Guinea pig)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343153(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataEC50:  5.30nMAssay Description:Agonist activity at muscarinic M3 receptor in guinea pig trachea assessed as bronchorelaxation activity in presence of propranololMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343160(N-(5-((R)-2-(6-(4-(3-((R)-3-(diisopropylamino)-1-p...)
Affinity DataEC50:  5.70nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343155(N-(5-((R)-2-(3-((R)-3-(diisopropylamino)-1-phenylp...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]N-methyl Scopolamine from human muscarinic M3 receptor expressed in CHO cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343153(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataEC50:  8.10nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343155(N-(5-((R)-2-(3-((R)-3-(diisopropylamino)-1-phenylp...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343157(N-(5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-p...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343154(2-(3-((R)-2-((R)-2-(3,5-dihydroxyphenyl)-2-hydroxy...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343152(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343156(N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343158(2-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-(4-(...)
Affinity DataEC50:  129nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343159(4-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phen...)
Affinity DataEC50:  173nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in CHO cells assessed as stimulation of intracellular cAMP production after 30 mins of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed