Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50032738
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333945BDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  0.75nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333945BDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333943BDBM50333943(N1-((2S,3S,5S)-5-((S)-1-(benzylamino)-3-methyl-1-o...)
Affinity DataKi:  3.30nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333945BDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  7nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333944BDBM50333944((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  13nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333943BDBM50333943(N1-((2S,3S,5S)-5-((S)-1-(benzylamino)-3-methyl-1-o...)
Affinity DataKi:  21nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333943BDBM50333943(N1-((2S,3S,5S)-5-((S)-1-(benzylamino)-3-methyl-1-o...)
Affinity DataIC50: 30nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333946BDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  34nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333943BDBM50333943(N1-((2S,3S,5S)-5-((S)-1-(benzylamino)-3-methyl-1-o...)
Affinity DataIC50: 38nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333944BDBM50333944((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333946BDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  56nMAssay Description:Inhibition of human plasma reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333944BDBM50333944((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataKi:  94nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333948BDBM50333948((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  130nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333946BDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  200nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333945BDBM50333945((S)-N-((S)-Benzylcarbamoyl-isopropylsulfanyl-methy...)
Affinity DataIC50: 240nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333947BDBM50333947((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  340nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333949BDBM50333949((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  450nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333949BDBM50333949((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  460nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333948BDBM50333948((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  760nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333951BDBM50333951((S)-2-{(S)-2-Hydroxy-2-[(S)-19-(methanesulfonyl-me...)
Affinity DataKi:  940nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333947BDBM50333947((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333949BDBM50333949((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333948BDBM50333948((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333946BDBM50333946((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333951BDBM50333951((S)-2-{(S)-2-Hydroxy-2-[(S)-19-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCathepsin D(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333950BDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetRenin(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333950BDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of reninMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333951BDBM50333951((S)-2-{(S)-2-Hydroxy-2-[(S)-19-(methanesulfonyl-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333950BDBM50333950((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50333947BDBM50333947((S)-2-{(S)-2-Hydroxy-2-[(S)-18-(methanesulfonyl-me...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed