Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50032750
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334153(CHEMBL1645164 | methyl 2-((4-(3-(4-bromophenyl)-3-...)
Affinity DataIC50:  860nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334157(3-(4-methoxyphenyl)-1-(4-((6-methylbenzo[d]oxazol-...)
Affinity DataIC50:  1.16E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334156(3-(4-fluorophenyl)-1-(4-((6-methylbenzo[d]oxazol-2...)
Affinity DataIC50:  1.29E+3nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50117922((1S,2S)-2-(2-((3-(1H-benzo[d]imidazol-2-yl)propyl)...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334155(CHEMBL1645167 | methyl 2-((4-(3-(4-fluorophenyl)-3...)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334153(CHEMBL1645164 | methyl 2-((4-(3-(4-bromophenyl)-3-...)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334156(3-(4-fluorophenyl)-1-(4-((6-methylbenzo[d]oxazol-2...)
Affinity DataIC50:  2.27E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334157(3-(4-methoxyphenyl)-1-(4-((6-methylbenzo[d]oxazol-...)
Affinity DataIC50:  2.48E+3nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334155(CHEMBL1645167 | methyl 2-((4-(3-(4-fluorophenyl)-3...)
Affinity DataIC50:  3.83E+3nMAssay Description:Inhibition of human hERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334151(CHEMBL1645161 | methyl 2-((4-(3-(4-chlorophenyl)-3...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334154(CHEMBL1645166 | methyl 2-((4-(3-phenyl-3-(4-(trifl...)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334152(CHEMBL1645163 | methyl 2-((4-(3-(4-bromophenyl)-3-...)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of T-type alpha1G calcium channel expressed in HEK293 cells assessed as Kcl-induced depolarizaionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataKd:  530nMAssay Description:Binding affinity to T-type alpha1G calcium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)
Affinity DataKd:  40nMAssay Description:Inhibition of T-type alpha1G calcium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1I(Homo sapiens (Human))
Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)
Affinity DataKd:  840nMAssay Description:Binding affinity to T-type alpha1I calcium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank