Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50039339
LigandChemical structure of BindingDB Monomer ID 50335008BDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50: 83nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335006BDBM50335006(2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl...)
Affinity DataIC50: 100nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335008BDBM50335008(5-Biphenyl-4-yl-4-(2-fluorophenyl)-N-methyl-4H-1,2...)
Affinity DataIC50: 110nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335001BDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335004BDBM50335004(3-Biphenyl-4-yl-4-(2-chlorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 190nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335010BDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50: 220nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335010BDBM50335010(3-Biphenyl-4-yl-5-ethyl-4-(2-fluorophenyl)-1,2,4-t...)
Affinity DataIC50: 230nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335007BDBM50335007(2-(3-(biphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 240nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335006BDBM50335006(2-(3-Biphenyl-4-yl-5-methyl-4H-1,2,4-triazole-4-yl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335004BDBM50335004(3-Biphenyl-4-yl-4-(2-chlorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 280nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335012BDBM50335012(3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2...)
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335001BDBM50335001(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 340nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335011BDBM50335011(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-...)
Affinity DataIC50: 370nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335005BDBM50335005(3-Biphenyl-4-yl-5-methyl-4-[2-(trifluoromethyl)phe...)
Affinity DataIC50: 390nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335009BDBM50335009(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methoxy-4H-1,...)
Affinity DataIC50: 510nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335005BDBM50335005(3-Biphenyl-4-yl-5-methyl-4-[2-(trifluoromethyl)phe...)
Affinity DataIC50: 600nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335007BDBM50335007(2-(3-(biphenyl-4-yl)-5-methyl-4H-1,2,4-triazol-4-y...)
Affinity DataIC50: 680nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335012BDBM50335012(3-Biphenyl-4-yl-5-methyl-4-(2-methylphenyl)-4H-1,2...)
Affinity DataIC50: 780nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50334998BDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50: 880nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335013BDBM50335013(3-Biphenyl-4-yl-4-(2-ethylphenyl)-5-methyl-4H-1,2,...)
Affinity DataIC50: 920nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335009BDBM50335009(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-methoxy-4H-1,...)
Affinity DataIC50: 990nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335023BDBM50335023(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-(methylsulfan...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50334998BDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114035BDBM50114035(3-Biphenyl-4-yl-4-(2-methoxy-phenyl)-5-methyl-4H-[...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50114035BDBM50114035(3-Biphenyl-4-yl-4-(2-methoxy-phenyl)-5-methyl-4H-[...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335022BDBM50335022(3-Biphenyl-4-yl-4-(2-fluorophenyl)-4H-1,2,4-triazo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335026BDBM50335026(3-Biphenyl-4-yl-5-tert-butyl-4-(2-fluorophenyl)-4H...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335002BDBM50335002(3-Biphenyl-4-yl-4-(3-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335011BDBM50335011(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-isopropyl-4H-...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335014BDBM50335014(3-Biphenyl-4-yl-5-methyl-4-(2-propylphenyl)-4H-1,2...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50334999BDBM50334999(3-Biphenyl-4-yl-4-cyclohexyl-5-methyl-4H-1,2,4-tri...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335024BDBM50335024(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-(methylsulfon...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335018BDBM50335018(3-(4-Cyclohexylphenyl)-4-(2-fluorophenyl)-5-methyl...)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335025BDBM50335025(3-Biphenyl-4-yl-4-(2-fluorophenyl)-5-trifluorometh...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335016BDBM50335016(4-Biphenyl-2-yl-3-biphenyl-4-yl-5-methyl-4H-1,2,4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335015BDBM50335015(3-Biphenyl-4-yl-4-(2-isopropylphenyl)-5-methyl-4H-...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335021BDBM50335021(3-(Biphenyl-4-yl-methyl)-4-(2-fluorophenyl)-5-meth...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335003BDBM50335003(3-Biphenyl-4-yl-4-(4-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335000BDBM50335000(3-Biphenyl-4-yl-4-isopropyl-5-methyl-4H-1,2,4-tria...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335019BDBM50335019(3-Biphenyl-2-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335020BDBM50335020(3-Biphenyl-3-yl-4-(2-fluorophenyl)-5-methyl-4H-1,2...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50335017BDBM50335017(4-(2-Fluorophenyl)-3-methyl-5-phenyl-4H-1,2,4-tria...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed