Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50032773
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334401(10-[3-(2-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334417(10-Piperidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-...)
Affinity DataEC50:  2.85E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334403(5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyc...)
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334404(10-(3-Phenoxy-azetidin-1-yl)-6,7,8,9-tetrahydro-5H...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334405(10-[3-(4-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334406(10-[3-(3-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334407(10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334408(CHEMBL1643674 | Ethyl-(6,7,8,9-tetrahydro-5H-1,4,7...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334409(10-[3-(3-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334410(10-[3-(2-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  84nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334411(10-[3-(4-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  95nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334412(CHEMBL1643858 | N-Methyl-N-{4-[1-(6,7,8,9-tetrahyd...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334413(10-[3-(Pyridin-3-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  211nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334414(CHEMBL1643673 | Ethyl-methyl-(6,7,8,9-tetrahydro-5...)
Affinity DataEC50:  362nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334415(10-[3-(Pyridin-4-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  574nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334416(10-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a...)
Affinity DataEC50:  764nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334417(10-Piperidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-...)
Affinity DataEC50:  4.56E+3nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334405(10-[3-(4-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334406(10-[3-(3-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334409(10-[3-(3-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334413(10-[3-(Pyridin-3-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334408(CHEMBL1643674 | Ethyl-(6,7,8,9-tetrahydro-5H-1,4,7...)
Affinity DataEC50:  138nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334417(10-Piperidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-...)
Affinity DataEC50:  585nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334401(10-[3-(2-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  648nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334403(5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyc...)
Affinity DataEC50:  762nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334415(10-[3-(Pyridin-4-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  1.23E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334412(CHEMBL1643858 | N-Methyl-N-{4-[1-(6,7,8,9-tetrahyd...)
Affinity DataEC50:  2.05E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334416(10-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a...)
Affinity DataEC50:  2.31E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334402(10-Azetidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-t...)
Affinity DataEC50:  2.35E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334411(10-[3-(4-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  2.63E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334410(10-[3-(2-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  2.68E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334407(10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  5.17E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334404(10-(3-Phenoxy-azetidin-1-yl)-6,7,8,9-tetrahydro-5H...)
Affinity DataEC50:  7.77E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334406(10-[3-(3-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334403(5-[1-(6,7,8,9-Tetrahydro-5H-1,4,7,10a-tetraaza-cyc...)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334402(10-Azetidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-t...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334401(10-[3-(2-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  94nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334405(10-[3-(4-Fluoro-phenoxy)-azetidin-1-yl]-6,7,8,9-te...)
Affinity DataEC50:  163nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334409(10-[3-(3-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  215nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334404(10-(3-Phenoxy-azetidin-1-yl)-6,7,8,9-tetrahydro-5H...)
Affinity DataEC50:  218nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334410(10-[3-(2-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  379nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334411(10-[3-(4-Methoxy-phenoxy)-azetidin-1-yl]-6,7,8,9-t...)
Affinity DataEC50:  503nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334408(CHEMBL1643674 | Ethyl-(6,7,8,9-tetrahydro-5H-1,4,7...)
Affinity DataEC50:  602nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334407(10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  706nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334414(CHEMBL1643673 | Ethyl-methyl-(6,7,8,9-tetrahydro-5...)
Affinity DataEC50:  842nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334415(10-[3-(Pyridin-4-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  1.16E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334412(CHEMBL1643858 | N-Methyl-N-{4-[1-(6,7,8,9-tetrahyd...)
Affinity DataEC50:  1.18E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334413(10-[3-(Pyridin-3-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  1.48E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334416(10-Pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a...)
Affinity DataEC50:  2.24E+3nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334402(10-Azetidin-1-yl-6,7,8,9-tetrahydro-5H-1,4,7,10a-t...)
Affinity DataEC50:  5.40nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed