Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 50032714
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333649((3R,6R)-6-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-(3-(...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333647(CHEMBL1642763 | Estradiol phosphate)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataIC50:  2.78E+4nMAssay Description:Inhibition of recombinant SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)
Affinity DataIC50:  4.04E+4nMAssay Description:Inhibition of recombinant SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  4.58E+4nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50071055((6bS,8aS,11R,12aR,12bS,14aR)-3-Hydroxy-4,6b,8a,11,...)
Affinity DataIC50:  6.16E+4nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)
Affinity DataIC50:  6.24E+4nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  6.54E+4nMAssay Description:Inhibition of recombinant SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50071058((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Affinity DataIC50:  7.57E+4nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)
Affinity DataIC50:  1.53E+5nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333647(CHEMBL1642763 | Estradiol phosphate)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant HePTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333647(CHEMBL1642763 | Estradiol phosphate)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333647(CHEMBL1642763 | Estradiol phosphate)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant SHP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333648(CHEMBL1642764)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333646(Bis-(2-chloro-ethyl)-carbamic acid 17-hydroxy-13-m...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of recombinant SHP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)
Affinity DataKd:  8.40E+3nMAssay Description:Binding affinity to recombinant SHP2 by surface plasmon responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed