Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50033276
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342639BDBM50342639(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-methyltetra...)
Affinity DataKi:  0.0360nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342638BDBM50342638(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(3-methoxypent...)
Affinity DataKi:  0.0390nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342625BDBM50342625(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-methoxyprop...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342634BDBM50342634(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-methoxyprop...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342636BDBM50342636(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-ethoxypropa...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342630BDBM50342630(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2,2,2-trifluo...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342612BDBM50342612(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2,2,2-trifluo...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342633BDBM50342633(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(methoxymethyl...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342637BDBM50342637(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-(2,2,2-trif...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342632BDBM50342632(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2,2,2-trifluo...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342635BDBM50342635(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-hydroxyprop...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342624BDBM50342624(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(methoxymethyl...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342629BDBM50342629(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-methoxyprop...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342631BDBM50342631(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2,2,2-trifluo...)
Affinity DataKi:  0.480nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342626BDBM50342626(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2,2,2-trifluo...)
Affinity DataKi:  0.610nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342628BDBM50342628(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(methoxymethyl...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342627BDBM50342627(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(1-(trifluorom...)
Affinity DataKi:  0.630nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342623BDBM50342623(N-((6S,9R)-6-(2,3-difluorophenyl)-3-isopropyl-6,7,...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224431BDBM50224431(N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-t...)
Affinity DataKi:  0.800nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342611BDBM50342611(N-((6S,9R)-3-cyclopropyl-6-(2,3-difluorophenyl)-6,...)
Affinity DataKi:  1nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342622BDBM50342622(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(thiazol-2-yl)...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342621BDBM50342621(N-((6S,9R)-6-(2,3-difluorophenyl)-3-phenyl-6,7,8,9...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342617BDBM50342617(N-((6S,9R)-6-(2,3-difluorophenyl)-3-methyl-6,7,8,9...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342618BDBM50342618(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(hydroxymethyl...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342620BDBM50342620((6S,9R)-6-(2,3-difluorophenyl)-N,N-dimethyl-9-(4-(...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342613BDBM50342613(N-((6S,9R)-6-(2,3-difluorophenyl)-6,7,8,9-tetrahyd...)
Affinity DataKi:  3.10nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342615BDBM50342615(N-((6S,9R)-6-(2,3-difluorophenyl)-2-(hydroxymethyl...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342614BDBM50342614(N-((6S,9R)-6-(2,3-difluorophenyl)-2-(2,2,2-trifluo...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342616BDBM50342616(N-((6S,9R)-6-(2,3-difluorophenyl)-2-methyl-6,7,8,9...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342619BDBM50342619(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2-(methylamin...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [125I]-CGRP from human recombinant CGRP receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342630BDBM50342630(N-((6S,9R)-6-(2,3-difluorophenyl)-3-(2,2,2-trifluo...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed