Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50004525
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483746(CHEMBL1770758)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483742(CHEMBL1770898)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483743(CHEMBL1770899)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483760(CHEMBL1770893)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483743(CHEMBL1770899)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483760(CHEMBL1770893)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483756(CHEMBL1770885)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483756(CHEMBL1770885)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483742(CHEMBL1770898)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483759(CHEMBL1770760)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483759(CHEMBL1770760)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483753(CHEMBL1770897)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483746(CHEMBL1770758)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483755(CHEMBL1770761)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483736(CHEMBL1770888)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483754(CHEMBL1770759)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483753(CHEMBL1770897)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483747(CHEMBL1770883)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483752(CHEMBL1770159)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483750(CHEMBL1770887)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483752(CHEMBL1770159)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483754(CHEMBL1770759)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483750(CHEMBL1770887)
Affinity DataIC50: 7nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483749(CHEMBL1770886)
Affinity DataIC50: 7.80nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483740(CHEMBL1770895)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483738(CHEMBL1770891)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483748(CHEMBL1770884)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483757(CHEMBL1770890)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483736(CHEMBL1770888)
Affinity DataIC50: 12nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483749(CHEMBL1770886)
Affinity DataIC50: 13nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483755(CHEMBL1770761)
Affinity DataIC50: 15nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483747(CHEMBL1770883)
Affinity DataIC50: 20nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483737(CHEMBL1770889)
Affinity DataIC50: 22nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483740(CHEMBL1770895)
Affinity DataIC50: 29nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483738(CHEMBL1770891)
Affinity DataIC50: 40nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483751(CHEMBL1770894)
Affinity DataIC50: 46nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483757(CHEMBL1770890)
Affinity DataIC50: 51nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483745(CHEMBL1770757)
Affinity DataIC50: 53nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483737(CHEMBL1770889)
Affinity DataIC50: 55nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483744(CHEMBL1770755)
Affinity DataIC50: 58nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483741(CHEMBL1770896)
Affinity DataIC50: 65nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483741(CHEMBL1770896)
Affinity DataIC50: 73nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483758(CHEMBL1770756)
Affinity DataIC50: 83nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483751(CHEMBL1770894)
Affinity DataIC50: 90nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483745(CHEMBL1770757)
Affinity DataIC50: 114nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483748(CHEMBL1770884)
Affinity DataIC50: 226nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483744(CHEMBL1770755)
Affinity DataIC50: 263nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483758(CHEMBL1770756)
Affinity DataIC50: 306nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483739(CHEMBL1770892)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of gamma-secretase in human H4 cells expressing APP Swedish mutant assessed as inhibition of amyloid beta (1 to 40) production by whole ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50483739(CHEMBL1770892)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of gamma-secretase in human HeLa cells assessed as inhibition of amyloid beta (1 to 40) production by DELFIA-based immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed