Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 50032981
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337332(2-(4-chlorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337333(2-(4-fluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337334(2-(4-chloro-2,6-difluorophenyl)-1-(4-(4-(5-methyl-...)
Affinity DataIC50:  1nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337336(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337335((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337337(2-(4-methoxyphenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337338(2-(2,6-difluoro-4-methoxyphenyl)-1-(4-(4-(5-methyl...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337339(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  2nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337340((2-bromophenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylamin...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337341((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337342(2-(2,6-difluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazo...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337343(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337344((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337345((2-methoxyphenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylam...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337346((4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337347(2-(2-fluorophenyl)-1-(4-(4-(5-methyl-1H-pyrazol-3-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337348(4-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337349(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337350(2-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337351((2-chlorophenyl)(4-(4-(5-methyl-1H-pyrazol-3-ylami...)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337352(CHEMBL1682370 | N,N-dimethyl-4-(4-(5-methyl-1H-pyr...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337353(1-(4-(4-(5-(1-methylcyclopropyl)-1H-pyrazol-3-ylam...)
Affinity DataIC50:  22nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337354(1-(4-(4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[1,2...)
Affinity DataIC50:  22nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337355(CHEMBL1682368 | N-(5-methyl-1H-pyrazol-3-yl)-2-(pi...)
Affinity DataIC50:  31nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337356(2-phenyl-1-(4-(4-(thiazol-2-ylamino)pyrrolo[1,2-f]...)
Affinity DataIC50:  59nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337357(1-(4-(4-(1-isopropyl-1H-imidazol-4-ylamino)pyrrolo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337358(2-phenyl-1-(4-(4-(pyridin-2-ylamino)pyrrolo[1,2-f]...)
Affinity DataIC50:  190nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337359(CHEMBL1682362 | N-cyclopropyl-3-(2-(4-(2-phenylace...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337331(1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrro...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of JAK2 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50337331(1-(4-(4-(5-methyl-1,3,4-thiadiazol-2-ylamino)pyrro...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of JAK3 after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed