Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50033198
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341234(4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)py...)
Affinity DataIC50: 139nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341234(4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)py...)
Affinity DataIC50: 245nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341235(4-(aminomethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyr...)
Affinity DataIC50: 788nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341236(4-((2-chloroacetamido)methyl)-N-(4-methyl-3-(4-(py...)
Affinity DataIC50: 788nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341236(4-((2-chloroacetamido)methyl)-N-(4-methyl-3-(4-(py...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341235(4-(aminomethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyr...)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341238(4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341238(4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...)
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341237(4-(but-2-enamidomethyl)-N-(4-methyl-3-(4-(pyridin-...)
Affinity DataIC50: 4.71E+3nMAssay Description:Inhibition of human wild type KIT assessed as [gamma33P]ATP incorporation into polyGluTyr after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341237(4-(but-2-enamidomethyl)-N-(4-methyl-3-(4-(pyridin-...)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of human wild type PDGFRalpha assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341234(4-(chloromethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)py...)
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341236(4-((2-chloroacetamido)methyl)-N-(4-methyl-3-(4-(py...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341237(4-(but-2-enamidomethyl)-N-(4-methyl-3-(4-(pyridin-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341238(4-(methacrylamidomethyl)-N-(4-methyl-3-(4-(pyridin...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50341235(4-(aminomethyl)-N-(4-methyl-3-(4-(pyridin-3-yl)pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human wild type ABL1 assessed as [gamma33P]ATP incorporation into poly-Ala-Glu-Lys-Tyr after 60 mins by microplate scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed