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Found 45 Enz. Inhib. hit(s) with all data for entry = 50033101
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339570(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50:  400nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339571(4-{4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]...)
Affinity DataIC50:  600nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339571(4-{4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339572(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50:  900nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339573(4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339574(5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339575(4-(4-Biphenyl-4-yl-[1,2,3]triazol-1-ylmethyl)-3-ni...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339574(5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339576(4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triaz...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339575(4-(4-Biphenyl-4-yl-[1,2,3]triazol-1-ylmethyl)-3-ni...)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339577(4-[2'-(2-Chloro-5-trifluoromethyl-phenoxymethyl)-b...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339575(4-(4-Biphenyl-4-yl-[1,2,3]triazol-1-ylmethyl)-3-ni...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339578(Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Tria...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339570(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339572(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339579(4-(4-Phenanthren-9-yl-phenyl)-1-(3-phenyl-propyl)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339578(Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Tria...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339580(4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339581(4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339582(4-[2'-(2-Chloro-5-trifluoromethyl-phenoxymethyl)-b...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339583(4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339576(4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339573(4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339584(4-(4'-Phenoxy-biphenyl-4-yl)-1-(3-phenyl-propyl)-1...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human recombinant 5-lipooxygenase expressed in Escherichia coli MV1190 by cell free assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339579(4-(4-Phenanthren-9-yl-phenyl)-1-(3-phenyl-propyl)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339580(4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339581(4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339577(4-[2'-(2-Chloro-5-trifluoromethyl-phenoxymethyl)-b...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339582(4-[2'-(2-Chloro-5-trifluoromethyl-phenoxymethyl)-b...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339583(4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339584(4-(4'-Phenoxy-biphenyl-4-yl)-1-(3-phenyl-propyl)-1...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339573(4'-[1-(2-o-Tolyl-ethyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339576(4-(5-Benzyl-3-phenylsulfanylmethyl-3H-[1,2,3]triaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339583(4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339574(5-Dimethylamino-naphthalene-1-sulfonic acid{4'-[1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339584(4-(4'-Phenoxy-biphenyl-4-yl)-1-(3-phenyl-propyl)-1...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339582(4-[2'-(2-Chloro-5-trifluoromethyl-phenoxymethyl)-b...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339577(4-[2'-(2-Chloro-5-trifluoromethyl-phenoxymethyl)-b...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339581(4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]-1-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339580(4'-[1-(3-Phenyl-propyl)-1H-[1,2,3]triazol-4-yl]-bi...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339578(Benzoic acid 1-Phenylsulfanylmethyl-1H-[1,2,3]Tria...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339579(4-(4-Phenanthren-9-yl-phenyl)-1-(3-phenyl-propyl)-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339570(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339572(4'-(1-Phenylsulfanylmethyl-1H-[1,2,3]triazol-4-yl)...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase 2(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50339571(4-{4-[2'-(Naphthalen-1-yloxymethyl)-biphenyl-4-yl]...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Prostaglandin E2 synthase-1 in IL-1beta stimulated microsomal fraction of human A549 cell assessed as PGE2 level by RP-HPLCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed