Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50033282
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342746(2-thienyl-sulfonamido-farnesylcysteine | CHEMBL177...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342745((R)-2-(5-(dimethylamino)naphthalene-1-sulfonamido)...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342747(3-nitrophenyl-sulfonamido-farnesylcysteine | CHEMB...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342748(4-fluoro-phenyl-sulfonamido-farnesylcysteine | CHE...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342744(phenyl-sulfonamido-farnesylcysteine | CHEMBL177129...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50342743((R)-2-(2-phenoxyphenylsulfonamido)-3-(3,7,11-trime...)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human ICMT incubated with N-Acetyl-S-farnesyl-L-cysteine substrate for 5 mins followed by addition of [14C]-SAM measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed