Compile Data Set for Download or QSAR
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Found 15 Enz. Inhib. hit(s) with all data for entry = 50033186
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341125(CHEMBL1760371 | N-(3-tert-butyl-5-(4-methyl-1H-imi...)
Affinity DataIC50:  20.1nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
Affinity DataIC50:  39.3nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341124(CHEMBL1760370 | N-(3-isopropyl-5-(4-methyl-1H-imid...)
Affinity DataIC50:  177nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341121(4-methyl-N-(3-(1-methyl-1H-1,2,3-triazol-4-yl)-5-(...)
Affinity DataIC50:  277nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM11(beta-cyclodextrin | betadex)
Affinity DataIC50:  309nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341119(4-methyl-N-(3-(3-methyl-1H-1,2,4-triazol-1-yl)-5-(...)
Affinity DataIC50:  480nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341120(4-methyl-N-(3-(1-methyl-1H-pyrazol-4-yl)-5-(triflu...)
Affinity DataIC50:  491nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341118(CHEMBL1760364 | N-(5-(1H-imidazol-1-yl)-3-(trifluo...)
Affinity DataIC50:  507nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341117(CHEMBL1760363 | N-(5-(4-methyl-1H-imidazol-1-yl)-3...)
Affinity DataIC50:  671nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341123(4-methyl-N-(3-methyl-5-(4-methyl-1H-imidazol-1-yl)...)
Affinity DataIC50:  774nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341127(CHEMBL1760373 | N-(3-chloro-5-(4-methyl-1H-imidazo...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341126(CHEMBL1760372 | N-[3-Adamantan-1-yl-5-(4-methyl-im...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341128(CHEMBL1760374 | N-(3-(4-methyl-1H-imidazol-1-yl)-5...)
Affinity DataIC50:  3.78E+3nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341129(4-ethyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(triflu...)
Affinity DataIC50:  5.51E+3nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50341122(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)-N-(...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Bcr/Abl by FRET-based Z-lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed