Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50033142
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340304(CHEMBL1760759 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340302(CHEMBL1760776 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340294(CHEMBL1760768 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340299(CHEMBL1760773 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340291((S)-2-((R)-2-(6-amino-5-cyclopropylpyrimidin-4-yl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340295(CHEMBL1760769 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340297(CHEMBL1760771 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340309((+/-)-N-(3-(2-(6-amino-5-cyclopropylpyrimidin-4-yl...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340308(CHEMBL1760763 | N-((2S)-3-(2-(5-cyclopropylpyrimid...)
Affinity DataIC50:  12nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340305(CHEMBL1760760 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340298(CHEMBL1760772 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340293((S)-2-((R)-2-(6-amino-5-cyclopropylpyrimidin-4-yl)...)
Affinity DataIC50:  19nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340306(CHEMBL1760761 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340307(CHEMBL1760762 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  38nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340303((S)-N-(2-ethoxyethyl)-N-(2-hydroxy-3-(9-(5-methyl-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340296(CHEMBL1760770 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  81nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340300(CHEMBL1760774 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340304(CHEMBL1760759 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  180nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340292((R)-2-((R)-2-(6-amino-5-cyclopropylpyrimidin-4-yl)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340306(CHEMBL1760761 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  310nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340309((+/-)-N-(3-(2-(6-amino-5-cyclopropylpyrimidin-4-yl...)
Affinity DataIC50:  470nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340302(CHEMBL1760776 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  490nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340291((S)-2-((R)-2-(6-amino-5-cyclopropylpyrimidin-4-yl)...)
Affinity DataIC50:  690nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340308(CHEMBL1760763 | N-((2S)-3-(2-(5-cyclopropylpyrimid...)
Affinity DataIC50:  740nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340294(CHEMBL1760768 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  900nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340301(CHEMBL1760775 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of Akt1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340295(CHEMBL1760769 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340303((S)-N-(2-ethoxyethyl)-N-(2-hydroxy-3-(9-(5-methyl-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340297(CHEMBL1760771 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340298(CHEMBL1760772 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340299(CHEMBL1760773 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340307(CHEMBL1760762 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340293((S)-2-((R)-2-(6-amino-5-cyclopropylpyrimidin-4-yl)...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340305(CHEMBL1760760 | N-(2-ethoxyethyl)-N-((2S)-2-hydrox...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340292((R)-2-((R)-2-(6-amino-5-cyclopropylpyrimidin-4-yl)...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340296(CHEMBL1760770 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50340300(CHEMBL1760774 | N-((S)-3-((R)-2-(6-amino-5-cyclopr...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of AKT1-mediated PRAS40 phosphorylation in human LNCaP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed