Compile Data Set for Download or QSAR
Report error Found 147 Enz. Inhib. hit(s) with all data for entry = 50033156
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10246BDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10246BDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340533BDBM50340533((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340530BDBM50340530((S)-1-(4-methoxybenzyl)-5-(2-((pyridin-3-yloxy)met...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340529BDBM50340529((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340543BDBM50340543((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340547BDBM50340547((4S,7S,10S,13S)-4-sec-butyl-7-(2-carboxyethyl)-13-...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of caspase 8 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340543BDBM50340543((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340542BDBM50340542((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340537BDBM50340537((S)-2-(1-(4-methoxybenzyl)-2-oxo-5-(2-((pyridin-3-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340542BDBM50340542((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340536BDBM50340536((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340540BDBM50340540((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340548BDBM50340548((4S,7S,10S,13S)-10-sec-butyl-7-(2-carboxyethyl)-13...)
Affinity DataIC50: 8nMAssay Description:Inhibition of caspase 6 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-1(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 10355BDBM10355(CHEMBL37630 | (3S)-3-[(2S)-2-[(2S)-2-[(2S)-2-aceta...)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of caspase 1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340526BDBM50340526((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-(phenoxymeth...)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340530BDBM50340530((S)-1-(4-methoxybenzyl)-5-(2-((pyridin-3-yloxy)met...)
Affinity DataIC50: 10.2nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273338BDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50: 10.8nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340531BDBM50340531((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: 10.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340541BDBM50340541((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340533BDBM50340533((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50: 11.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273338BDBM50273338((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50: 11.6nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340531BDBM50340531((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: 11.9nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340544BDBM50340544((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273337BDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50: 12.2nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340545BDBM50340545((S)-5-(2-((2,4-difluorophenoxy)methyl)pyrrolidin-1...)
Affinity DataIC50: 12.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273337BDBM50273337((S)-1-((1-(2-Fluoroethyl)-1H-[1,2,3]-triazol-4-yl)...)
Affinity DataIC50: 12.4nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340546BDBM50340546((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50: 13.4nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340532BDBM50340532((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 13.7nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340545BDBM50340545((S)-5-(2-((2,4-difluorophenoxy)methyl)pyrrolidin-1...)
Affinity DataIC50: 15.2nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340546BDBM50340546((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50: 15.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340544BDBM50340544((S)-5-(2-((2,4-difluorophenoxy)methyl)azetidin-1-y...)
Affinity DataIC50: 15.4nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340532BDBM50340532((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 17.6nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340529BDBM50340529((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-((pyridin-3-...)
Affinity DataIC50: 17.6nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340541BDBM50340541((S)-1-((1-(2-fluoroethyl)-1H-1,2,3-triazol-4-yl)me...)
Affinity DataIC50: 18nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340538BDBM50340538((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-(ph...)
Affinity DataIC50: 18.3nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340528BDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 19.2nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340534BDBM50340534((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-(ph...)
Affinity DataIC50: 22.4nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340539BDBM50340539((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50: 23.3nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340535BDBM50340535((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50: 24.4nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340526BDBM50340526((S)-1-(4-(2-fluoroethoxy)benzyl)-5-(2-(phenoxymeth...)
Affinity DataIC50: 26.1nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340540BDBM50340540((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50: 26.5nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340528BDBM50340528((S)-1-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzy...)
Affinity DataIC50: 26.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340527BDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: 27.9nMAssay Description:Inhibition of human caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340527BDBM50340527((S)-1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-5-(2-(p...)
Affinity DataIC50: 28.9nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340536BDBM50340536((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-((p...)
Affinity DataIC50: 45nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340537BDBM50340537((S)-2-(1-(4-methoxybenzyl)-2-oxo-5-(2-((pyridin-3-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340535BDBM50340535((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50: 68.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340539BDBM50340539((S)-2-(1-(4-(2-(2-fluoroethoxy)ethoxy)benzyl)-2-ox...)
Affinity DataIC50: 70nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50340538BDBM50340538((S)-2-(1-(4-(2-fluoroethoxy)benzyl)-2-oxo-5-(2-(ph...)
Affinity DataIC50: 96.3nMAssay Description:Inhibition of caspase 7 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
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