Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50033346
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as increase in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataEC50:  2.10nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataEC50:  5.10nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataEC50:  5.70nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50184359(MT-II | CHEMBL430239 | Ac-Nle-c[Asp-His-DPhe-Arg-T...)
Affinity DataIC50: 8nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343650((2S,5S,8R,11S,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as increase in intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343650((2S,5S,8R,11S,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 300nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343650((2S,5S,8R,11S,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 400nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343649((2S,5S,8S,11R,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 500nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343650((2S,5S,8R,11S,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 515nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343649((2S,5S,8S,11R,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at human MC5R expressed in HEK293 cells assessed as intracellular cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343650((2S,5S,8R,11S,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343648((2S,5S,8S,11R,14S,17S,20S)-11-((1H-imidazol-5-yl)m...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50343649((2S,5S,8S,11R,14S,17S,20S)-5-((1H-indol-3-yl)methy...)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by Wallac 1470 gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed