Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50033396
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344511(3-chloro-4-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-a...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344505(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  7nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344499((1S,5S)-8-(isobutylsulfonyl)-3-(5-methyl-6-(2-meth...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344510(4-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50341309(isopropyl 4-(5-methyl-6-(2-methylpyridin-3-yloxy)p...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344484((1S,5S)-tert-butyl 3-(5-methyl-6-(2-methylpyridin-...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344512((1R,5R)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344487((1S,5S)-1-methylcyclopropyl 3-(5-methyl-6-(2-methy...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344495((1S,5S)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-m...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344486((1S,5S)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344500((1S,5S)-8-(5-chlorothiophen-2-ylsulfonyl)-3-(5-met...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344498((1S,5S)-8-(butylsulfonyl)-3-(5-methyl-6-(2-methylp...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344498((1S,5S)-8-(butylsulfonyl)-3-(5-methyl-6-(2-methylp...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344492((1S,5S)-cyclobutyl 3-(5-methyl-6-(2-methylpyridin-...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344496((1S,5S)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyr...)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344509(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  34nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344490((1S,5S)-cyclopropylmethyl 3-(5-methyl-6-(2-methylp...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344513((1R,5R)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-m...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344491((1S,5S)-1-cyclopropylethyl 3-(5-methyl-6-(2-methyl...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344501((1S,5S)-8-(4-fluorophenylsulfonyl)-3-(5-methyl-6-(...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344504((1S,5S)-3-(6-(2-chlorophenoxy)-5-methylpyrimidin-4...)
Affinity DataEC50:  44nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344506(5-chloro-2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-a...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344512((1R,5R)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344496((1S,5S)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyr...)
Affinity DataEC50:  53nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344507(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3....)
Affinity DataEC50:  54nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344486((1S,5S)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3...)
Affinity DataEC50:  55nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344491((1S,5S)-1-cyclopropylethyl 3-(5-methyl-6-(2-methyl...)
Affinity DataEC50:  59nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344489((1S,5S)-2,2,2-trifluoroethyl 3-(5-methyl-6-(2-meth...)
Affinity DataEC50:  61nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344517((1R,3S,5R)-8-(cyclopropylsulfonyl)-6,6-difluoro-3-...)
Affinity DataEC50:  62nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344495((1S,5S)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-m...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344505(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  68nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344499((1S,5S)-8-(isobutylsulfonyl)-3-(5-methyl-6-(2-meth...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344485(isopropyl 4-(6-(2-fluoro-4-(methylsulfonyl)phenoxy...)
Affinity DataEC50:  82nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344504((1S,5S)-3-(6-(2-chlorophenoxy)-5-methylpyrimidin-4...)
Affinity DataEC50:  82nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344508(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344494((1S,5S)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyr...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344497((1S,5S)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyr...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344515((1R,3S,5R)-8-(cyclopropylsulfonyl)-6-fluoro-3-(5-m...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344488((1S,5S)-ethyl 3-(5-methyl-6-(2-methylpyridin-3-ylo...)
Affinity DataEC50:  131nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344511(3-chloro-4-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-a...)
Affinity DataEC50:  140nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344500((1S,5S)-8-(5-chlorothiophen-2-ylsulfonyl)-3-(5-met...)
Affinity DataEC50:  145nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344503(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo[3....)
Affinity DataEC50:  166nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344484((1S,5S)-tert-butyl 3-(5-methyl-6-(2-methylpyridin-...)
Affinity DataEC50:  176nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344508(2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  180nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344517((1R,3S,5R)-8-(cyclopropylsulfonyl)-6,6-difluoro-3-...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344510(4-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-azabicyclo...)
Affinity DataEC50:  220nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344513((1R,5R)-8-(cyclopropylsulfonyl)-3-(5-methyl-6-(2-m...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344497((1S,5S)-3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyr...)
Affinity DataEC50:  250nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344506(5-chloro-2-(6-((1S,5S)-8-(cyclopropylsulfonyl)-8-a...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344484((1S,5S)-tert-butyl 3-(5-methyl-6-(2-methylpyridin-...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
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