Compile Data Set for Download or QSAR
maximum 50k data
Found 25 Enz. Inhib. hit(s) with all data for entry = 50033403
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Affinity DataKi:  1.03nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
TargetD(4) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(CHEMBL1779060 | N-(2-(2-methoxy-5-methylbenzamido)...)
Affinity DataKi:  7.60nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(CHEMBL1779059 | N-(2-(4-methoxy-3-phenethoxyphenyl...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]SCH233930 from human D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  93nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  209nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  1.72E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  1.96E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi:  2.37E+3nMAssay Description:Antagonist activity at histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50137617(CHEMBL64260 | N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-i...)
Affinity DataKi:  2.85E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50137617(CHEMBL64260 | N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-i...)
Affinity DataKi:  3.76E+3nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(CHEMBL1779060 | N-(2-(2-methoxy-5-methylbenzamido)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(CHEMBL1779059 | N-(2-(4-methoxy-3-phenethoxyphenyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344630(CHEMBL1779058 | N-(4-(4-Fluoro)butyrophenone)-4-az...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D5 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344629(CHEMBL1779059 | N-(2-(4-methoxy-3-phenethoxyphenyl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50344628(CHEMBL1779060 | N-(2-(2-methoxy-5-methylbenzamido)...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50137617(CHEMBL64260 | N-[2-(6,7-Dimethoxy-3,4-dihydro-1H-i...)
Affinity DataKi:  1.04E+4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]SCH233930 from human D1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
The University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50170660(CHEMBL190883 | CHEMBL521582 | N,N-dipropyl-2-[4-me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed