Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50033802
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 20182BDBM20182((1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-6-hydroxy-6-me...)
Affinity DataIC50: 300nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351538BDBM50351538(CHEMBL1824673)
Affinity DataIC50: 700nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351539BDBM50351539(CHEMBL1824674)
Affinity DataIC50: 900nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351538BDBM50351538(CHEMBL1824673)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351541BDBM50351541(CHEMBL1824676)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351540BDBM50351540(CHEMBL1824675)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351534BDBM50351534(CHEMBL1824669)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351535BDBM50351535(CHEMBL1824670)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351529BDBM50351529(CHEMBL1824664)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351536BDBM50351536(CHEMBL1824671)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 78179BDBM78179(SMR000221636 | CHEMBL1621019 | 4-(4-methylphenyl)-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351521BDBM50351521(CHEMBL1824658)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351537BDBM50351537(CHEMBL1824672)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351542BDBM50351542(CHEMBL1824661)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351533BDBM50351533(CHEMBL1824668)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351531BDBM50351531(CHEMBL1824666)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351530BDBM50351530(CHEMBL1824665)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351526BDBM50351526(CHEMBL1616869)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 78179BDBM78179(SMR000221636 | CHEMBL1621019 | 4-(4-methylphenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351528BDBM50351528(CHEMBL1824663)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 93773BDBM93773(SMR000177579 | cid_2852359 | 4-[4-(4-Chloro-phenyl...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351524BDBM50351524(CHEMBL1824660)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351527BDBM50351527(CHEMBL1824662)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351532BDBM50351532(CHEMBL1824667)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351518BDBM50351518(CHEMBL1824655)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351519BDBM50351519(CHEMBL1824656)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351523BDBM50351523(CHEMBL1824659)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351522BDBM50351522(CHEMBL1300882 | cid_715106)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351520BDBM50351520(CHEMBL1824657)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed