Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 35nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 45nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 87nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 89nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 124nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 137nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 174nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 217nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 218nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 249nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 258nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 259nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 276nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 296nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 342nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 352nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 385nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 851nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 854nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 871nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5-HT2A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 2.01E+3nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 2.80E+3nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 4.20E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic beta2 receptor expressed in HEK293 cells co-transfected with Galpha16 assessed as inhibition of adrenaline-induced ...More data for this Ligand-Target Pair
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic Alpha-1D receptor expressed in HEK293 cells co-transfected with Galpha16 assessed as inhibition of adrenaline-induc...More data for this Ligand-Target Pair
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic Alpha-1B receptor expressed in CHO cells assessed as inhibition of adrenaline-induced intracellular calcium after 3...More data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic alpha1A receptor expressed in CHO cells assessed as inhibition of adrenaline-induced intracellular calcium level af...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 320nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Soochow University College Of Pharmaceutical Sciences
Curated by ChEMBL
Affinity DataEC50: 190nMAssay Description:Agonist activity at 5-HT1A receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair