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Found 41 Enz. Inhib. hit(s) with all data for entry = 50033634
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50263467(11-Butyryloxy-N-n-propylnoraporphine | CHEMBL47867...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348766(CHEMBL1806876)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348765(CHEMBL1806875)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50263467(11-Butyryloxy-N-n-propylnoraporphine | CHEMBL47867...)
Affinity DataKi:  56nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50007427((R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348770(CHEMBL1806864)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348772(CHEMBL1806866)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348768(CHEMBL1806814)
Affinity DataKi:  94nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348762(CHEMBL1806868)
Affinity DataKi:  96nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348763(CHEMBL1806869)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataKi:  137nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataKi:  174nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348761(CHEMBL1806867)
Affinity DataKi:  217nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348768(CHEMBL1806814)
Affinity DataKi:  218nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348774(CHEMBL1806879)
Affinity DataKi:  249nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348769(CHEMBL1806863)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  259nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348767(CHEMBL1806877)
Affinity DataKi:  276nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348765(CHEMBL1806875)
Affinity DataKi:  296nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348766(CHEMBL1806876)
Affinity DataKi:  342nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348767(CHEMBL1806877)
Affinity DataKi:  352nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348773(CHEMBL1806878)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348771(CHEMBL1806865)
Affinity DataKi:  385nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348764(CHEMBL1806872)
Affinity DataKi:  851nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50007427((R) 6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)
Affinity DataKi:  854nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348762(CHEMBL1806868)
Affinity DataKi:  871nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]ketanserin from 5-HT2A receptor expressed in CHO cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348763(CHEMBL1806869)
Affinity DataKi:  2.01E+3nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  2.20E+3nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  2.40E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348761(CHEMBL1806867)
Affinity DataKi:  2.80E+3nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  4.20E+3nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348760(CHEMBL1806871)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor expressed in HEK293 cells after 50 mins by beta liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic beta2 receptor expressed in HEK293 cells co-transfected with Galpha16 assessed as inhibition of adrenaline-induced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic Alpha-1D receptor expressed in HEK293 cells co-transfected with Galpha16 assessed as inhibition of adrenaline-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic Alpha-1B receptor expressed in CHO cells assessed as inhibition of adrenaline-induced intracellular calcium after 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at adrenergic alpha1A receptor expressed in CHO cells assessed as inhibition of adrenaline-induced intracellular calcium level af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataEC50:  320nMAssay Description:Agonist activity at dopamine D2 receptor expressed in HEK293 cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Soochow University College Of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50348759(CHEMBL1806874)
Affinity DataEC50:  190nMAssay Description:Agonist activity at 5-HT1A receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed