Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50033705
TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50349933(CHEMBL1812144)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50349934(CHEMBL1812139)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50349932(CHEMBL1812137)
Affinity DataIC50: 4.88E+3nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 6.03E+4nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pBR322 DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)