Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50033831
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352142(CHEMBL1824770)
Affinity DataIC50: 69nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352145(CHEMBL1824773)
Affinity DataIC50: 134nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352143(CHEMBL1824771)
Affinity DataIC50: 155nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82106(6,8,10-Traiazaspiro[4.5]deca-6,8-diene-7,9-diamine...)
Affinity DataIC50: 173nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352144(CHEMBL1824772)
Affinity DataIC50: 548nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM82113(1,3,5-Triazaspiro[5.5]undeca-1,3-diene-2,4-diamine...)
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352146(CHEMBL1824776)
Affinity DataIC50: 5.33E+3nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352132(CHEMBL1824519)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352136(CHEMBL1824531)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352137(CHEMBL1824532)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352138(CHEMBL535030)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352139(CHEMBL1824533)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352133(CHEMBL1824528)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352134(CHEMBL1824529)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352135(CHEMBL1824530)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352140(CHEMBL1824534)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352141(CHEMBL1824535)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM18069(CHEMBL22 | TMP | Trimethoprim (TMP) | 5-[(3,4,5-tr...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352128(CHEMBL1824523)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352129(CHEMBL1824522)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352130(CHEMBL1824521)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352131(CHEMBL1824520)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352124(CHEMBL1824527)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352125(CHEMBL1824526)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352126(CHEMBL1824525)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50352127(CHEMBL1824524)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human DHFR assessed as NADPH consumption for conversion of dihydrofolic acid to tetrahydrofolic acid after 6 mins every 5 sec by UV-Vis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed