Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50034126
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357489BDBM50357489(CHEMBL1914472)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]BMS-599240 from recombinant human BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357489BDBM50357489(CHEMBL1914472)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357483BDBM50357483(CHEMBL1914607)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357476BDBM50357476(CHEMBL1917907)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357491BDBM50357491(CHEMBL1917913)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357488BDBM50357488(CHEMBL1917902)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]BMS-599240 from recombinant human BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357474BDBM50357474(CHEMBL1917905)
Affinity DataIC50: 8nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16047BDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357474BDBM50357474(CHEMBL1917905)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357488BDBM50357488(CHEMBL1917902)
Affinity DataIC50: 11nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by ELI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357482BDBM50357482(CHEMBL1917916)
Affinity DataIC50: 12nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357490BDBM50357490(CHEMBL1917912)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357475BDBM50357475(CHEMBL1917906)
Affinity DataIC50: 17nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357476BDBM50357476(CHEMBL1917907)
Affinity DataIC50: 20nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357480BDBM50357480(CHEMBL1917914)
Affinity DataIC50: 45nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357472BDBM50357472(CHEMBL1917903)
Affinity DataIC50: 54nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357481BDBM50357481(CHEMBL1917915)
Affinity DataIC50: 68nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357470BDBM50357470(CHEMBL1917900)
Affinity DataIC50: 88nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357472BDBM50357472(CHEMBL1917903)
Affinity DataIC50: 110nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357475BDBM50357475(CHEMBL1917906)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357477BDBM50357477(CHEMBL1917908)
Affinity DataIC50: 140nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357471BDBM50357471(CHEMBL1917901)
Affinity DataIC50: 141nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357484BDBM50357484(CHEMBL1914608)
Affinity DataIC50: 330nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357473BDBM50357473(CHEMBL1917904)
Affinity DataIC50: 600nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357487BDBM50357487(CHEMBL1915988)
Affinity DataIC50: 720nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357478BDBM50357478(CHEMBL1917909)
Affinity DataIC50: 870nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357486BDBM50357486(CHEMBL1915987)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357479BDBM50357479(CHEMBL1917910)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357485BDBM50357485(CHEMBL1917911)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357486BDBM50357486(CHEMBL1915987)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of BACE-1 in human HEK293 cells overexpressing APP 695 swedish mutation assessed as inhibition of amyloid beta (1 to 40) production by imm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357487BDBM50357487(CHEMBL1915988)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed