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Found 75 Enz. Inhib. hit(s) with all data for entry = 50034064
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356215(CHEMBL1910473)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356214(CHEMBL1910471)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356209(CHEMBL1910466)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356210(CHEMBL1910467)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356208(CHEMBL1910465)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356222(CHEMBL1910648)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356218(CHEMBL1910476)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356206(CHEMBL1910459)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356216(CHEMBL1910474)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356221(CHEMBL1910647)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356219(CHEMBL1910649)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356220(CHEMBL1910650)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356203(CHEMBL1910472)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM24047((2R)-3-methyl-2-[(4-{4-[(3-methyl-1-benzofuran-2-y...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356213(CHEMBL1910470)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356207(CHEMBL1910460)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356204(CHEMBL1910453)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356205(CHEMBL1910458)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356242(CHEMBL1910461)
Affinity DataIC50:  9.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356217(CHEMBL1910475)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356203(CHEMBL1910472)
Affinity DataIC50:  310nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356222(CHEMBL1910648)
Affinity DataIC50:  400nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356224(CHEMBL1910449)
Affinity DataIC50:  420nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356223(CHEMBL1910651)
Affinity DataIC50:  420nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356224(CHEMBL1910449)
Affinity DataIC50:  450nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356242(CHEMBL1910461)
Affinity DataIC50:  500nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356218(CHEMBL1910476)
Affinity DataIC50:  540nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24047((2R)-3-methyl-2-[(4-{4-[(3-methyl-1-benzofuran-2-y...)
Affinity DataIC50:  700nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356219(CHEMBL1910649)
Affinity DataIC50:  760nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356214(CHEMBL1910471)
Affinity DataIC50:  800nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356206(CHEMBL1910459)
Affinity DataIC50:  800nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356207(CHEMBL1910460)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356205(CHEMBL1910458)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356215(CHEMBL1910473)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356223(CHEMBL1910651)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356216(CHEMBL1910474)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356225(CHEMBL1910439)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356210(CHEMBL1910467)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356203(CHEMBL1910472)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of aggrecanase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356209(CHEMBL1910466)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356221(CHEMBL1910647)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356217(CHEMBL1910475)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356246(CHEMBL1910652)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24047((2R)-3-methyl-2-[(4-{4-[(3-methyl-1-benzofuran-2-y...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of aggrecanase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356246(CHEMBL1910652)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356234(CHEMBL1910448)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50356211(CHEMBL1910468)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24031((2R)-2-{[4-(4-hydroxyphenyl)benzene]sulfonamido}-3...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50356211(CHEMBL1910468)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of aggrecanase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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