Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50034542
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363993(CHEMBL1950044)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human Aurora A assessed as inhibition of [gamma-33P]ATP incorporation into substrate after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363992(CHEMBL1950043)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human Aurora A assessed as inhibition of [gamma-33P]ATP incorporation into substrate after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363992(CHEMBL1950043)
Affinity DataKi:  2.72E+4nMAssay Description:Mixed type inhibition of human aurora A using kemptide as a substrate by double reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363992(CHEMBL1950043)
Affinity DataKi:  3.15E+4nMAssay Description:Non-competitive inhibition of human aurora-A using kemptide as a substrate by double reciprocal plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM60927(ANS | BDBM50126831 | 1-anilinonaphthalene-8-sulfon...)
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to human Cdk2 by fluorescence spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363995(CHEMBL1950040)
Affinity DataIC50: 9.10E+4nMAssay Description:Inhibition of human Aurora A assessed as inhibition of [gamma-33P]ATP incorporation into substrate after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363996(CHEMBL1950041)
Affinity DataIC50: 1.37E+5nMAssay Description:Inhibition of human Aurora A assessed as inhibition of [gamma-33P]ATP incorporation into substrate after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363997(CHEMBL1950042)
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibition of human Aurora A assessed as inhibition of [gamma-33P]ATP incorporation into substrate after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arizona

Curated by ChEMBL
LigandPNGBDBM50363994(CHEMBL1950039)
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of human Aurora A assessed as inhibition of [gamma-33P]ATP incorporation into substrate after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed