Compile Data Set for Download or QSAR
Report error Found 44 Enz. Inhib. hit(s) with all data for entry = 50034210
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  4.71nMAssay Description:Inhibition of human factor 10a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358889BDBM50358889(CHEMBL1923563)
Affinity DataIC50: 7nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50328724BDBM50328724((S)-N2,N2-dimethyl-N5-((2-methylbenzofuran-5-ylami...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358887BDBM50358887(CHEMBL1923561)
Affinity DataIC50: 10nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358884BDBM50358884(CHEMBL1923469)
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358888BDBM50358888(CHEMBL1923562)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358885BDBM50358885(CHEMBL1923470)
Affinity DataIC50: 14nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358871BDBM50358871(CHEMBL1923457)
Affinity DataIC50: 14nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358869BDBM50358869(CHEMBL1923454)
Affinity DataIC50: 19nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358882BDBM50358882(CHEMBL1923467)
Affinity DataIC50: 22nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26351BDBM26351(CHEMBL196803 | 2-{[(2-methyl-1-benzofuran-5-yl)ami...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358886BDBM50358886(CHEMBL1923560)
Affinity DataIC50: 32nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358870BDBM50358870(CHEMBL1923455)
Affinity DataIC50: 32nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358867BDBM50358867(CHEMBL1923453)
Affinity DataIC50: 32nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358872BDBM50358872(CHEMBL1923456)
Affinity DataIC50: 51nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358875BDBM50358875(CHEMBL1923461)
Affinity DataIC50: 58nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358863BDBM50358863(CHEMBL1923448)
Affinity DataIC50: 60nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358859BDBM50358859(CHEMBL1923444)
Affinity DataIC50: 61nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358877BDBM50358877(CHEMBL1923462)
Affinity DataIC50: 121nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358862BDBM50358862(CHEMBL1923447)
Affinity DataIC50: 122nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358874BDBM50358874(CHEMBL1923459)
Affinity DataIC50: 129nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358873BDBM50358873(CHEMBL1923458)
Affinity DataIC50: 130nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358880BDBM50358880(CHEMBL1923465)
Affinity DataIC50: 209nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358876BDBM50358876(CHEMBL1923460)
Affinity DataIC50: 337nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358878BDBM50358878(CHEMBL1923463)
Affinity DataIC50: 674nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358868BDBM50358868(CHEMBL1923452)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358860BDBM50358860(CHEMBL1923445)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358856BDBM50358856(CHEMBL1923441)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.28E+3nMAssay Description:Inhibition of human TPA by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358881BDBM50358881(CHEMBL1923466)
Affinity DataIC50: 1.33E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358865BDBM50358865(CHEMBL1923450)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358864BDBM50358864(CHEMBL1923449)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358879BDBM50358879(CHEMBL1923464)
Affinity DataIC50: 1.96E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358866BDBM50358866(CHEMBL1923451)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358861BDBM50358861(CHEMBL1923446)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  3.28E+3nMAssay Description:Inhibition of human alpha-thrombin by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  3.68E+3nMAssay Description:Inhibition of human factor 7a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358857BDBM50358857(CHEMBL1923442)
Affinity DataIC50: 9.75E+3nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358858BDBM50358858(CHEMBL1923443)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of human factor 10a using phenyl-Ile-Glu-Gly-Arg-pNA as substrate preincubated for 3 mins prior to substrate addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.33E+4nMAssay Description:Inhibition of human factor 11a by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.51E+4nMAssay Description:Inhibition of human u-PA by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of human plasmin by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetVitamin K-dependent protein C(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50358883BDBM50358883(CHEMBL1923468)
Affinity DataKi:  2.25E+4nMAssay Description:Inhibition of human activated protein C by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed