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Found 26 Enz. Inhib. hit(s) with all data for entry = 50034547
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364041(CHEMBL1950551)
Affinity DataIC50:  2nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364040(CHEMBL1950550)
Affinity DataIC50:  5nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50:  13nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364042(CHEMBL1950552)
Affinity DataIC50:  22nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364039(CHEMBL1950549)
Affinity DataIC50:  26nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase 5(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50:  32nMAssay Description:Inhibition of human SCD5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50:  41nMAssay Description:Inhibition of human SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50362592(CHEMBL1938870)
Affinity DataIC50:  68nMAssay Description:Inhibition of SCD1 in rat hepatocytes expressing OATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364041(CHEMBL1950551)
Affinity DataIC50:  91nMAssay Description:Inhibition of SCD1 in rat hepatocytes expressing OATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364040(CHEMBL1950550)
Affinity DataIC50:  176nMAssay Description:Inhibition of SCD1 in rat hepatocytes expressing OATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50:  213nMAssay Description:Inhibition of SCD1 in rat hepatocytes expressing OATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364035(CHEMBL1950545)
Affinity DataIC50:  226nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364037(CHEMBL1950547)
Affinity DataIC50:  248nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364038(CHEMBL1950548)
Affinity DataIC50:  305nMAssay Description:Inhibition of rat liver microsome SCD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364042(CHEMBL1950552)
Affinity DataIC50:  945nMAssay Description:Inhibition of SCD1 in rat hepatocytes expressing OATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364041(CHEMBL1950551)
Affinity DataIC50:  969nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50362592(CHEMBL1938870)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364040(CHEMBL1950550)
Affinity DataIC50:  3.87E+3nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50:  7.74E+3nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA (8-3)-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of delta-5 desaturase expressed in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA 6-desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364036(CHEMBL1950546)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of delta-6 desaturase expressed in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364042(CHEMBL1950552)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364037(CHEMBL1950547)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364035(CHEMBL1950545)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364039(CHEMBL1950549)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50364038(CHEMBL1950548)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SCD1 in OATP-deficient human HepG2 cells by whole cell assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed