Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50034412
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361993BDBM50361993(CHEMBL1939700)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334158BDBM50334158(CHEMBL2314421 | CHEMBL1645202 | 1'-benzyl-3-(2-flu...)
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361998BDBM50361998(CHEMBL1939698)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361992BDBM50361992(CHEMBL1939699)
Affinity DataKi: >1nMAssay Description:Binding affinity to VAChTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299280BDBM50299280(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)
Affinity DataKi: >1nMAssay Description:Binding affinity to VAChTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361994BDBM50361994(CHEMBL1939701)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361992BDBM50361992(CHEMBL1939699)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299280BDBM50299280(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVesicular acetylcholine transporter(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334158BDBM50334158(CHEMBL2314421 | CHEMBL1645202 | 1'-benzyl-3-(2-flu...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to VAChTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50338990BDBM50338990(CHEMBL2311153 | N-phenylpropyl-N''-3,4-dimethoxyph...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to EBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361997BDBM50361997(CHEMBL1939704)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361995BDBM50361995(CHEMBL1939702)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50120482BDBM50120482(1'-benzylspiro[1,3-dihydroisobenzofuran-1,4'-(hexa...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50035131BDBM50035131((1S,9S,13S)-1,13-dimethyl-10-(3-methylbut-2-enyl)-...)
Affinity DataKi:  5.70nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21398BDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361996BDBM50361996(CHEMBL1939703)
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain homogenates after 180 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361998BDBM50361998(CHEMBL1939698)
Affinity DataKi:  152nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299280BDBM50299280(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)
Affinity DataKi:  209nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334158BDBM50334158(CHEMBL2314421 | CHEMBL1645202 | 1'-benzyl-3-(2-flu...)
Affinity DataKi:  211nMAssay Description:Binding affinity to EBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361992BDBM50361992(CHEMBL1939699)
Affinity DataKi:  233nMAssay Description:Binding affinity to EBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299280BDBM50299280(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)
Affinity DataKi:  246nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299280BDBM50299280(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)
Affinity DataKi:  368nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334158BDBM50334158(CHEMBL2314421 | CHEMBL1645202 | 1'-benzyl-3-(2-flu...)
Affinity DataKi:  372nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361992BDBM50361992(CHEMBL1939699)
Affinity DataKi:  419nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299280BDBM50299280(1'-benzyl-3-(3-fluoropropyl)-3H-spiro[[2]benzofura...)
Affinity DataKi:  455nMAssay Description:Binding affinity to EBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334158BDBM50334158(CHEMBL2314421 | CHEMBL1645202 | 1'-benzyl-3-(2-flu...)
Affinity DataKi:  456nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361998BDBM50361998(CHEMBL1939698)
Affinity DataKi:  481nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361992BDBM50361992(CHEMBL1939699)
Affinity DataKi:  605nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361998BDBM50361998(CHEMBL1939698)
Affinity DataKi:  918nMAssay Description:Binding affinity to kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50361992BDBM50361992(CHEMBL1939699)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute of Radiopharmacy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334158BDBM50334158(CHEMBL2314421 | CHEMBL1645202 | 1'-benzyl-3-(2-flu...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed