Compile Data Set for Download or QSAR
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Found 7 Enz. Inhib. hit(s) with all data for entry = 8241
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataKi:  8.50E+4nMpH: 7.0Assay Description:Progress curves for slow-binding inhibition analysis were obtained by adding nitrocefin (final concentration 36 μM) to a solution containing enz...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataIC50:  1.59E+5nMpH: 7.0Assay Description:Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataIC50:  1.68E+5nMpH: 7.0Assay Description:Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataIC50:  2.04E+5nMpH: 7.0Assay Description:Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataIC50:  2.35E+5nMpH: 7.0Assay Description:Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataIC50:  2.90E+5nMpH: 7.0Assay Description:Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus anthracis)
Baylor University

LigandPNGBDBM50335803(3-hydroxy-2-methyl-4H-pyran-4-thione | CHEMBL16506...)
Affinity DataIC50:  3.67E+5nMpH: 7.0Assay Description:Bla2, in 50 mM MOPS and 30% (v/v) glycerol, was assayed for substrate activity by adding enzyme at a final concentration of 0.13 μg/mL to soluti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed