Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50039824
TargetAdenosine receptor A1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163460(2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-(3-trifluoro...)
Affinity DataKi:  14.1nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163453(2-Amino-4-(3-difluoromethoxy-phenyl)-6-(2-hydroxy-...)
Affinity DataKi:  39.8nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163452(2-Amino-4-(3-fluoro-phenyl)-6-(2-hydroxy-ethylsulf...)
Affinity DataKi:  39.8nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50163462(2-Amino-6-(2-hydroxy-ethylsulfanyl)-4-m-tolyl-pyri...)
Affinity DataKi:  81.3nMAssay Description:Antagonist activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM5380(2,4-Disubstituted Pyrimidine 2d | N-(3,5-dimethylp...)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50384799(CHEMBL2037483)
Affinity DataIC50:  20nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM5400(2,4-Disubstituted Pyrimidine 5b | N-(3,5-dimethylp...)
Affinity DataIC50:  2.39E+3nMAssay Description:Antagonist activity at VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19828((1R,2R)-2-{[(3-chlorophenyl)sulfanyl]methyl}-N-(cy...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19817((1R,2R)-N-(cyanomethyl)-2-[(phenylsulfanyl)methyl]...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50207446(2-(2-(2-chloro-6-fluorophenylamino)-5-methylphenyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
TargetProcathepsin L(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19817((1R,2R)-N-(cyanomethyl)-2-[(phenylsulfanyl)methyl]...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM50049661(3''''-Fluoro-4''''-methoxy-[1,1'';2'',1'''']terphe...)
Affinity DataIC50:  7.16E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T

Curated by ChEMBL
LigandPNGBDBM19828((1R,2R)-2-{[(3-chlorophenyl)sulfanyl]methyl}-N-(cy...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed