Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50039709
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382684(CHEMBL2023158 | US9409868, 24)
Affinity DataIC50: 100nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382685(CHEMBL2023156 | US9409868, 22)
Affinity DataIC50: 260nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)
Affinity DataIC50: 650nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382686(CHEMBL2023154 | US9409868, 18)
Affinity DataIC50: 670nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382687(CHEMBL2023152 | US9409868, 16)
Affinity DataIC50: 800nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382688(CHEMBL2023155 | US9409868, 19)
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382689(CHEMBL2023153 | US9409868, 17)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382685(CHEMBL2023156 | US9409868, 22)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382690(CHEMBL2023160 | US9409868, 26)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382691(CHEMBL2023151 | US9409868, 15)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382684(CHEMBL2023158 | US9409868, 24)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382689(CHEMBL2023153 | US9409868, 17)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382692(CHEMBL2023150)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382688(CHEMBL2023155 | US9409868, 19)
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382687(CHEMBL2023152 | US9409868, 16)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382693(CHEMBL2023159 | US9409868, 25)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382691(CHEMBL2023151 | US9409868, 15)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382692(CHEMBL2023150)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382690(CHEMBL2023160 | US9409868, 26)
Affinity DataIC50: 5.36E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50196697(1-benzyl-3-(1H-indazol-5-yl)urea | N-benzyl-N0-(1H...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382694(CHEMBL2023149 | US9409868, 13)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382695(CHEMBL2023157 | US9409868, 23)
Affinity DataIC50: 7.52E+3nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382695(CHEMBL2023157 | US9409868, 23)
Affinity DataIC50: 9.07E+3nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50196697(1-benzyl-3-(1H-indazol-5-yl)urea | N-benzyl-N0-(1H...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382693(CHEMBL2023159 | US9409868, 25)
Affinity DataIC50: 1.98E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382694(CHEMBL2023149 | US9409868, 13)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382696(CHEMBL2023161 | US9409868, 27)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382696(CHEMBL2023161 | US9409868, 27)
Affinity DataIC50: 3.29E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382697(CHEMBL2023147 | US9409868, 10)
Affinity DataIC50: 3.61E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50246684(N-(1H-indazol-5-yl)acetamide | CHEMBL503641)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50279877(N-Pyridin-4-yl-nicotinamide | CHEMBL67352 | US9409...)
Affinity DataIC50: 5.59E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382697(CHEMBL2023147 | US9409868, 10)
Affinity DataIC50: 5.91E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382698(CHEMBL2023148 | US9409868, 11)
Affinity DataIC50: 6.18E+4nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50246684(N-(1H-indazol-5-yl)acetamide | CHEMBL503641)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382699(CHEMBL2022282 | US9409868, 4)
Affinity DataIC50: 7.25E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50279877(N-Pyridin-4-yl-nicotinamide | CHEMBL67352 | US9409...)
Affinity DataIC50: 7.55E+4nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50304148(CHEMBL17551 | 1H-indazol-5-amine | cid_88012 | 1H-...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382698(CHEMBL2023148 | US9409868, 11)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50304148(CHEMBL17551 | 1H-indazol-5-amine | cid_88012 | 1H-...)
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382699(CHEMBL2022282 | US9409868, 4)
Affinity DataIC50: 2.21E+5nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382700(CHEMBL1566648 | US9409868, 5)
Affinity DataIC50: 2.70E+5nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382700(CHEMBL1566648 | US9409868, 5)
Affinity DataIC50: 3.57E+5nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382702(CHEMBL2023145 | US9409868, 7)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382702(CHEMBL2023145 | US9409868, 7)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382701(CHEMBL2023144 | US9409868, 6)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human His-puritin-tagged ROCK1 expressed in Sf9 cells after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

Curated by ChEMBL
LigandPNGBDBM50382701(CHEMBL2023144 | US9409868, 6)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of ROCK2 after 1 hr by FRET-based enzyme-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed