Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50034651
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant PI3Kdelta HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant PI3Kalpha by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant PI3Kbeta HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50315213(TCMDC-137004 | 2-(difluoromethyl)-1-(4,6-dimorphol...)
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant PI3Kgamma HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50365736(CHEMBL1956189)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50365735(MKT-077 | CHEMBL33859 | US20230414581, Compound 39)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Tianjin Key Laboratory On Technologies Enabling Development of Clinical Therapeutics and Diagnostics

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of telomeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed