Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50039751
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383315BDBM50383315(CHEMBL2029773)
Affinity DataKi:  0.400nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383327BDBM50383327(CHEMBL2029772)
Affinity DataKi:  1.80nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383321BDBM50383321(CHEMBL2029780)
Affinity DataKi:  3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383323BDBM50383323(CHEMBL2029778)
Affinity DataKi:  4nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383325BDBM50383325(CHEMBL2029776)
Affinity DataKi:  4.40nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383324BDBM50383324(CHEMBL2029777)
Affinity DataKi:  6nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383319BDBM50383319(CHEMBL2029782)
Affinity DataKi:  12nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383328BDBM50383328(CHEMBL2029771)
Affinity DataKi:  18nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383322BDBM50383322(CHEMBL2029779)
Affinity DataKi:  19nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by Dixon an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383326BDBM50383326(CHEMBL2029775)
Affinity DataKi:  29nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383318BDBM50383318(CHEMBL2029783)
Affinity DataKi:  30nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383314BDBM50383314(CHEMBL2029774)
Affinity DataKi:  76nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383329BDBM50383329(CHEMBL2029770)
Affinity DataKi:  180nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383320BDBM50383320(CHEMBL2029781)
Affinity DataKi:  200nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383317BDBM50383317(CHEMBL2029784)
Affinity DataKi:  250nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383316BDBM50383316(CHEMBL2029785)
Affinity DataKi:  450nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383330BDBM50383330(CHEMBL2029769)
Affinity DataKi:  1.10E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytosolic beta-glucosidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383315BDBM50383315(CHEMBL2029773)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human cytosolic beta-glucosidase using 4-methylumbelliferyl beta-D-glucopyranoside as substrate after 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50383331BDBM50383331(CHEMBL2029768)
Affinity DataKi:  2.70E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
University of British Columbia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50182798BDBM50182798(1,5-Dideoxy-1,5-imino-D-xylitol | PIPERIDINE-3,4,5...)
Affinity DataKi:  2.80E+3nMpH: 5.0Assay Description:Competitive inhibition of wild type human glucocerebrosidase using 2,4-dinitrophenyl beta-D-glucopyranoside as substrate after 3 mins by Dixon and Li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed